In the ever-evolving landscape of HIV research and treatment, the 30th International Workshop on HIV Drug Resistance and Treatment Strategies awarded Nália Ismael an award for Best Oral Abstract. Nalia is a PhD student at Stellenbosch University in the Faculty of Medicine and Health Science ...
In the ever-evolving landscape of HIV research and treatment, the 30th International Workshop on HIV Drug Resistance and Treatment Strategies awarded Nália Ismael an award for Best Oral Abstract. Nalia is a PhD student at Stellenbosch University in the Faculty of Medicine and Health Science. Her research on antiretroviral drug resistance and treatment strategies, particularly in Mozambique, earned her this accolade.
The International Workshop on HIV Drug Resistance and Treatment Strategies is a global stage for unveiling the latest advancements in the fight against HIV. Bringing together experts, innovators, and passionate individuals from around the world, this event is a crucible of knowledge and collaboration.
Nália Ismael's award-winning study has unveiled crucial insights into the effectiveness of treatment regimens in Mozambique, a region with unique challenges in managing HIV. In Mozambique, where approximately 2.2 million people live with HIV, including 150,000 children aged 14 and younger, Nália Ismael's research carries immense significance. Her findings have the potential to shape the future of HIV treatment and care in this region and beyond. The study investigated the HIVDR rate and patterns in clients with virologic failure after switching to the new regimen,Tenofovir, Lamivudine, and Dolutegravir (TLD) from another first line Antiretroviral therapy (ART).
According to her supervisor, Prof. Wolfgang Preiser, Medical Virology Professor at Stellenbosch University Faculty of Medicine and Health Sciences, "Nália's work is a testament to the importance of on-the-ground research in areas most affected by HIV. Her findings will undoubtedly guide better treatment approaches in Mozambique and beyond."
The study was done in collaboration with the Elizabeth Glaser Pediatric AIDS Foundation (EGPAF) and the Centre for Disease Control and Prevention (CDC). Results indicated that intensive counseling played a pivotal role in achieving viral suppression for most individuals post-transition, demonstrating its efficacy in Mozambique. However, a concerning trend was observed: a high rate of resistance to dolutegravir (DTG) (an antiretroviral drug) among patients with non-suppressed viral loads. Nália Ismael's research underscored the importance of drug resistance surveillance as a tool for ongoing monitoring, enabling more informed decisions regarding effective treatment regimens.
Nália's co-supervisor, Prof. Tulio de Oliveira, a Bioinformatics Professor at Stellenbosch University offered his perspective, stating, HIVdrugresistance.png"Nália's dedication and insights reflect the spirit of our collaborative efforts. Her work has the potential to influence not only Mozambique but also global strategies for managing HIV, emphasizing the importance of staying ahead of drug resistance."
In her own words, Nalia humbly expressed her surprise: "This award was unexpected as a first-time presenter, and I am immensely grateful to the study team, my supervisors and funders for their unwavering support."
Nália Ismael's recognition serves as a reminder of the incredible dedication and talent present in the field of HIV research. It is through the tireless efforts of individuals like her that we can continue to progress in the fight against HIV, offering hope and better treatment options to millions of people worldwide. Her work not only contributes to our understanding of HIV drug resistance but also offers real hope for a brighter future in the global fight against this devastating disease. Congratulations, Nália Ismael, on this well-deserved honor!
News date: 2023-11-07
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KRISP has been created by the coordinated effort of the University of KwaZulu-Natal (UKZN), the Technology Innovation Agency (TIA) and the South African Medical Research Countil (SAMRC).
Location: K-RITH Tower Building
Nelson R Mandela School of Medicine, UKZN
719 Umbilo Road, Durban, South Africa.
Director: Prof. Tulio de Oliveira