BIOTOOLS SPOTLIGHT






KRISP BIOTOOLS INTRODUCTION:

KRISP host many of the tools that were developed in Bioafrica.net (Prof. Tulio de Oliveira old group website). The great majority of our tools are freely and openly accessible. In addition, we also provide a linux cluster so the tools can be used free of charge.


Booster: a new bootstrap method for construction of large trees

A new version of the phylogenetic bootstrap in which the presence of inferred branches in replications is measured using a gradual 'transfer' distance rather than the binary presence or absence index used in Felsenstein's original version. The resulting supports are higher and do not induce falsely supported branches.



Genome Detective

This is the first version of our Arbovirus typing tool for Chikungunya, Dengue, Yellow Fever and Zika



Genome Detective Chikungunya Typing Tool

This is the first version of the Chikungunya typing tool, which uses phylogenetic analysis to identify the species and genotype of the virus.



Genome Detective Dengue Virus Typing Tool

This is a beta version of our Dengue Virus Typing tool. For the mean time, this tool should be used for evaluation only. Please send feedback to Tulio de Oliveira.



Genome Detective Yellow Fever Virus Typing Tool

This is the first version of the Yellow Fever typing tool, which uses phylogenetic analysis to identify the species and genotype of the virus.



Genome Detective Zika Typing Tool

This is the first version of the Zika typing tool, which uses phylogenetic analysis to identify the species and genotype of the virus.



Genome Detective Coronavirus Typing Tool

Genome Detective Coronavirus Typing Tool for rapid identification and characterization of novel coronavirus genomes



Genome Detective HBV Subtyping Tool V2 - South African mirror

Phylogenetic tool to identify the Hepatitis B Virus (HBV) subtypes and recombinants. Query sequences are analysed for recombination using bootscanning methods.



Genome Detective HCV Typing Tool

This is a beta version of our HCV Typing tool. For the mean time, this tool should be used for evaluation only. Please send feedback to Tulio de Oliveira.



HIV Quality Analysis Tool

Tool to determine quality and contamination of sequences using local Blast



HIV-1 proteomics resource: combining protein data with bioinformatics tools

Contains information about each HIV-1 gene product in regard to expression, functional activities, and interactions with viral and host macromolecules



HTLV 1 & 2 Typing Tool

This is a beta version of our HTLV 1 & 2 Typing tool. For the mean time, this tool should be used for evaluation only. Please send feedback to Tulio de Oliveira.



Phylotype Online Tool

Online web interface that provides an interface to identify phylotypes and allows for exploratory analyses of very large data sets.



REGA HIV Subtyping Tool V3 - Belgium Mirror

Phylogenetic tool to identify the HIV-1 subtypes and recombinants. Query sequences are analysed for recombination using bootscanning methods. The version 3 contains new CRFs (CRF01_AE to CRF47_BF).



REGA HIV Subtyping Tool V3 - South African mirror

This tool is designed to use phylogenetic methods in order to identify the HIV-1 subtype of a specific sequence. The sequence is analysed for recombination using bootscanning methods. The version 3 contains new CRFs (CRF01_AE to CRF47_BF).



REGA HIV Subtyping Tool V3 - Stanford Mirror

Phylogenetic tool to identify the HIV-1 subtypes and recombinants. Query sequences are analysed for recombination using bootscanning methods. The version 3 contains new CRFs (CRF01_AE to CRF47_BF).



RNA Virus Database

The RNA Virus Database is a database and web application describing the genome organization and providing analytical tools for all known species of RNA virus.



SATuRN RegaDB Online tool

This database is a free password-protected open source database available. Access to the highly curated data sets is through applications that are reviewed by the SATuRN executive committee



Southern African Mirror of the Stanford HIV Drug Resistance Database (HIVDB)

A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance



KRISP High-Processing Computer Servers have > 300 Bioinformatics Software Applications

KRISP can provide computational services to both academic and to industrial partners. We have access to four HPCs (see KRISP Toys). We have access a wide range of standard life science applications (many optimized for the HPC environment) and databases are available. Additional applications or databases can be hosted on request. Arrangements can also be made to secure proprietary data. Please contact us to discuss collaborations, consultancy and grants applications.

Search installed software
Latest Installed Software
raxml-ng-0.6.0
Phylogeny/Generic
vfat
Assembler and Aligner/Assembler
sratoolkit.2.9.0
Assembler and Aligner/Generic
cdhit
Assembler and Aligner/Generic
FLASH-1.2.11
Assembler and Aligner/Quality Control
ncbi-blast-2.2.31+
Blast/Generic
blast-2.2.26
Blast/Generic
vprofiler
Development/Generic
miniconda2
Development/Multiple Sequence Alignment

KRISP has been created by the coordinated effort of the University of KwaZulu-Natal (UKZN), the Technology Innovation Agency (TIA) and the South African Medical Research Countil (SAMRC).


Location: K-RITH Tower Building
Nelson R Mandela School of Medicine, UKZN
719 Umbilo Road, Durban, South Africa.
Director: Prof. Tulio de Oliveira