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Title: Strengthening Genomic Surveillance Capacity for Epidemic-Prone Pathogens by Training Personnel From Public Health Laboratories in Brazil and Paraguay
Authors: Giovanetti M, Fonseca V, Navegantes W, Abreu AL, Stabeli R, Vazquez CC, Albuquerque CFC, Rico JM, Galiano SG, Almiron M, Alcantara LCJ.
Journal: Weekly Epidemiological Record,v. 98, p. 63-68: (2023)

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Abstract

Strengthening genomic surveillance is critical for tracking and responding to epidemic-prone pathogens, particularly in tropical and subtropical regions. This study describes the implementation of a genomic surveillance network between Brazil and Paraguay, aimed at enhancing the detection, monitoring, and response to viral threats. Since 2018, the initiative has trained over 600 public health professionals and sequenced more than 11,900 viral genomes, including dengue (DENV), chikungunya (CHIKV), Zika (ZIKV), yellow fever (YFV), West Nile virus (WNV), and SARS-CoV-2. Using Oxford Nanopore sequencing and bioinformatics approaches, this network facilitated real-time genomic monitoring, identification of novel viral strains, and phylogenetic assessments. The results demonstrated the effectiveness of portable sequencing technologies in strengthening regional surveillance, enabling the early detection of emerging viral threats, and informing public health policies. Expanding this model to other Latin American countries could enhance pandemic preparedness and outbreak control.

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Citation: Giovanetti M, Fonseca V, Navegantes W, Abreu AL, Stabeli R, Vazquez CC, Albuquerque CFC, Rico JM, Galiano SG, Almiron M, Alcantara LCJ. Strengthening Genomic Surveillance Capacity for Epidemic-Prone Pathogens by Training Personnel From Public Health Laboratories in Brazil and Paraguay Weekly Epidemiological Record,v. 98, p. 63-68: (2023).