NEWS SPOTLIGHT



the gem



mail and guardian



CLIMADE

KRISP NEWS


Building Africa’s Biotech Future

From site visits to start-up: how one African STARS fellow turned lessons in leadership and communication into two grants that will put African-made enzymes and gene tools on the map.


Teaching Africa to Compete Globally

On March 4 this year, Grace Bosco watched her own face appear on the Nasdaq Tower in Times Square – a name and a company logo, up in lights, next to just nine others chosen from thousands of entrepreneurs worldwide.


TB Genomics Spotlight

SU at Europe’s leading mycobacteriology conference.


AI, Innovation and the Future of Women’s Health

A peek inside the Gates Grand Challenges Annual Meeting 2026, where AI, maternal health, and climate science took centre stage.


Rewriting Africa’s Disease History

New review explores how ancient DNA preserved in archaeological remains could unlock new insights into the origins, evolution, and spread of infectious diseases, helping to inform future surveillance and epidemic preparedness across Africa.


Equipping Parliament for AI

As AI reshapes society, Stellenbosch University is helping Parliament prepare for responsible oversight and informed decision-making.


Tracking Rift Valley Fever

A new genomic study has mapped how Rift Valley fever virus has evolved across Africa over nearly 80 years, revealing how a handful of genetic changes could shape future outbreaks, vaccine development and disease surveillance.


PUBLICATIONS SPOTLIGHT


The Lancet


Science


Nature Medicine

KRISP SCIENTIFIC PUBLICATIONS


Addressing pandemic-wide systematic errors in the SARS-CoV-2 phylogeny.
Hunt M, Hinrichs A, Anderson D, Karim L, Dearlove B, Knaggs J, Constantinides B, Fowler P, Rodger G, Street T, Lumley S, Webster H, Sanderson T, Ruis C, Kotzen B, de Maio N, Amenga-Etego L, Amuzu D, Avaro M, Awandare G, Ayivor-Djanie R, Barkham T, Bashton M, Batty E, Bediako Y, De Belder D, Benedetti E, Bergthaler A, Boers S, Campos J, Carr R, Chen Y, Cuba F, Dattero M, Dejnirattisai W, Dilthey A, Duedu K, Endler L, Engelmann I, Francisco N, Fuchs J, Gnimpieba E, Groc S, Gyamfi J, Heemskerk D, Houwaart T, Hsiao N, Huska M, Hölzer M, Iranzadeh A, Jarva H, Jeewandara C, Jolly B, Joseph R, Kant R, Ki K, Kurkela S, Lappalainen M, Lataretu M, Lemieux J, Liu C, Malavige G, Mashe T, Mongkolsapaya J, Montes B, Mora J, Morang’a C, Mvula B, Nagarajan N, Nelson A, Ngoi J, da Paixão J, Panning M, Poklepovich T, Quashie P, Ranasinghe D, Russo M, San J, Sanderson N, Scaria V, Screaton G, Sessions O, Sironen T, Sisay A, Smith D, Smura T, Supasa P, Suphavilai C, Swann J, Tegally H, Tegomoh B, Vapalahti O, Walker A, Wilkinson R, Williamson C, Zair X, Biere B, Dürrwald R, Mache C, Oh D, Schulze J, Wedde M, Wolff T, Fuchs S, Semmler T, Paraskevopoulou S, Kerber R, Kröger S, Haas W, Bode K, Corman V, Erren M, Finzer P, Grosser R, Haffner M, Hermann B, Kiel C, Krumbholz A, Lorentz T, Meinck K, Nitsche A, Petzold M, Schwanz T, Szabados F, Tewald F, Tiemann C, de Oliveira T, Peto T, Crook D, Corbett-Detig R, Iqbal Z, Nature Methods (2026), 23:653-662.



Tracing the spatial origins and spread of SARS-CoV-2 Omicron lineages in South Africa.
Dor G, Wilkinson E, Martin DP, Moir M, Tshiabuila D, Kekana D, Ntozini B, Joseph R, Iranzadeh A, Nyaga MM, Goedhals D, Maponga T, Maritz J, Laguda-Akingba O, Ramphal Y, MacIntyre C, Chabuka L, Pillay S, Giandhari J, Baxter C, Hsiao NY, Preiser W, Bhiman JN, Davies MA, Venter M, Treurnicht FK, Wolter N, Williamson C, von Gottberg A, Lessells R, Tegally H, de Oliveira T, Nature Communications (2025), 28;16(1):4937. doi: 10.1038/s41467-025-60081-0:.



Genomic Surveillance of Climate-Amplified Cholera Outbreak, Malawi, 2022–2023.
Chabuka L, Choga W, Mavian C, Moir M, Morgenstern C, Tegaly H, Sharma A, Wilkinson E, Naidoo Y, Inward R, Bhatt S, WilliamWint G, Khan K, Bogoch I, Kraemer M, Lourenço J, Baxter C, Tagliamonte M, Salemi M, Lessells R, Mitambo C, Chitatanga R, Bitilinyu-Bango J, Chiwaula M, Chavula Y, Bukhu M, Manda H, Chitenje M, Malolo I, Mwanyongo A, Mvula B, Nyenje M, de Oliveira T, Kagoli M, Emerging Infectious Diseases (2025), 31(6):. doi: 10.3201/eid3106.240930.:.



Importance of outbreak response research in bridging knowledge gaps on emerging infectious diseases.
Breiman R, Osoro E, Reithinger R, Wang D, Diamond M, Van Voorhis W, Wasserheit J, Rabinowitz P, Mboup S, Hemingway-Foday J, de Oliveira T, Boon A, Schieffelin J, Sempowski G, Moody M, Vasilakis N, Hanley K, Nasimiyu C, Situma S, Ngere I, Kyobe Bosa H, Nyakarahuka L, Bakamutumaho B, Woodson S, Njenga M, BMJ Global Health (2025), 10(6):e018297. doi: 10.1136/bmjgh-2024-018297.:.



Artificial intelligence for modelling infectious disease epidemics.
Kraemer M, Tsui J, Chang S, Lytras S, Khurana M, Vanderslott S, Bajaj S, Scheidwasser N, Curran-Sebastian J, Semenova E, Zhang M, Unwin H, Watson O, Mills C, Dasgupta A, Ferretti L, Scarpino S, Koua E, Morgan O, Tegally H, Paquet U, Moutsianas L, Fraser C, Ferguson N, Topol E, Duchêne D, Stadler T, Kingori P, Parker M, Dominici F, Shadbolt N, Suchard M, Ratmann O, Flaxman S, Holmes E, Gomez-Rodriguez M, Schölkopf B, Donnelly C, Pybus O, Cauchemez S, Bhatt S, Nature (2025), :.



Spatiotemporal disease suitability prediction for Oropouche virus and the role of vectors across the Americas.
Poongavanan J, Dunaiski M, D’or G, Kraemer M, Giovanetti M, Lim A, Brady O, Baxter C, Fonseca V, Alcantara L, de Oliveira T, Tegally H, medRxiv (2025), doi: 10.1101/2025.02.28.25323068.:.



Characterization of SARS-CoV-2 intrahost genetic evolution in vaccinated and non-vaccinated patients from the Kenyan population.
Lugano D, Mwangi K, Mware B, Kibet G, Osiany S, Kiritu E, Dobi P, Muli C, Njeru R, de Oliveira T, Njenga M, Routh A, Oyola S, medRxiv (2025), doi: 10.1101/2025.03.03.25323296.:.



KRISP VIDEOS


COVID-19 | News sub-variant being monitored closely
By: Tulio De Oliveira and CERI and KRISP teams

KRISP BIOINFORMATICS TOOLS



Genome Detective Coronavirus Typing Tool

Genome Detective Coronavirus Typing Tool for rapid identification and characterization of novel coronavirus genomes



Genome Detective Dengue Virus Typing Tool

This is a beta version of our Dengue Virus Typing tool. For the mean time, this tool should be used for evaluation only. Please send feedback to Tulio de Oliveira.



Genome Detective Zika Typing Tool

This is the first version of the Zika typing tool, which uses phylogenetic analysis to identify the species and genotype of the virus.



Genome Detective Chikungunya Typing Tool

This is the first version of the Chikungunya typing tool, which uses phylogenetic analysis to identify the species and genotype of the virus.



Genome Detective Yellow Fever Virus Typing Tool

This is the first version of the Yellow Fever typing tool, which uses phylogenetic analysis to identify the species and genotype of the virus.



Genome Detective

This is the first version of our Arbovirus typing tool for Chikungunya, Dengue, Yellow Fever and Zika



REGA HIV Subtyping Tool V3 - Belgium Mirror

Phylogenetic tool to identify the HIV-1 subtypes and recombinants. Query sequences are analysed for recombination using bootscanning methods. The version 3 contains new CRFs (CRF01_AE to CRF47_BF).


MORE TOOLS


KRISP has been created by the coordinated effort of the University of KwaZulu-Natal (UKZN), the Technology Innovation Agency (TIA) and the South African Medical Research Countil (SAMRC).


Location: K-RITH Tower Building
Nelson R Mandela School of Medicine, UKZN
719 Umbilo Road, Durban, South Africa.
Director: Prof. Tulio de Oliveira