Videos Videos Descriptions

YouTube Video

Krisp - a next generation DNA sequencing research centre opens in Durban, South Africa - eTV news

Author: Tulio de Oliveira, Veron Ramsuran, Nicolette Crozier, Zandile Sibisi, Marcel Tongo, Benjamin Chimukangara, Thabiso Dlamini - Date: 2017-07-24

Krisp at South African eTV channel evenning news


YouTube Video

Transmission networks and risk of HIV infection in KwaZulu-Natal, South Africa: a community-wide phylogenetic study - Keynote presentation at AIDS 2016.

Author: Anthony Fauci, Quarraisha Abdool Karim, David Khanyile, Tulio de Oliveira, Salim Abdool Karim - Date: 2016-06-20

This is a short video of our keynote presentation at the AIDS 2016 conference in Durban.


YouTube Video

Completion of a world-class genomics lab at KRISP/UKZN, Durban, South Africa - Part III

Author: Prevashinee Padayachee and Tulio de Oliveira - Date: 2014-08-06

This short video diary is the third in a series that traced the creation of a world class DNA genomic facility in the African continent that focuses on research on diseases that affect human health. This video shows the completion of genomics centre. It shows Illumina Miseq and Life Technologies Next Generation (NextGen) sequencing Facilities used in HIV & TB research.


YouTube Video

KRISP Genomics Laboratory Construction - Video Diary Part II

Author: Prevashinee Padayachee and Tulio de Oliveira - Date: 2014-04-05

This short video diary is the second in a series of movies that will trace the transformation of our existing laboratory into a world class DNA genomic facility. The second video provides an introduction to the robotics system and present our new bioinformatics facility. The genomics facility is based at the College of Health Sciences, University of KwaZulu-Natal and funded by the Wellcome Trust Africa Centre, South Africa MRC, UKZN, NRF and BMGF. This will be one of the first facilities in the African continent that focuses on research on diseases that affect human health.


YouTube Video

KRISP Genomics Laboratory Construction - Video Diary Part I

Author: Prevashinee Padayachee and Tulio de Oliveira - Date: 2014-03-13

This short video diary is the first in a series of four weekly movies that will trace the transformation of our existing laboratory into a world class DNA genomic facility. This will be one of the first facilities in the African continent that focuses on research on diseases that affect human health. The first video provides an introduction to the series, a pictorial tour of the current facilities and outlines the exciting renovation plans that are under way. The genomics facility is based at the College of Health Sciences, University of KwaZulu-Natal and funded by the Wellcome Trust Africa Centre, South Africa MRC, UKZN, NRF and BMGF


YouTube Video

HIV-1 Drug Resistance in Children in rural South Africa

Author: Siva Danaviah - Date: 2014-03-01

In a short interview, Dr. Siva Danaviah describes drug resistance patterns in HIV-infected children on antiretroviral therapy (ART) and its impact to inform public health policies in high prevalence settings. The aim of this study was to characterise the acquired drug resistance in HIV-infected children failing first-line ART in a decentralised rural HIV program in South Africa


YouTube Video

Justen Manasa PhD thesis summary

Author: Justen Manasa - Date: 2013-11-29

This is a 8 minutes video that summarizes the PhD thesis of Justen Manasa. This video cover the affordable and open accessible SATuRN/Life Tech genotyping method, SATuRN data curation process using RegaDB and a number of manuscripts on transmitted and acquired resistance in rural South Africa.


YouTube Video

SATuRN RegaDB Data Curation Process

Author: Justen Manasa - Date: 2013-11-28

This is a short interview about the SATuRN datacuration manuscript, which has been published at DATABASES (Oxofrd) journal. In this video Justen Manasa describe access to the database, biocuration process and highlight examples of biological discoveries done with HIV drug resistance data stored at the SATuRN RegaDB database


YouTube Video

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings

Author: Manasa J, Danaviah S, Pillay S, Padayachee P, Mthiyane H, Seebregts C, Rinke De Wit TF, Viljoen J, Katzenstein D, De Oliveira T - Date: 2013-10-18

SATuRN/Life Technologies open access and affordable drug resistance genotyping system. This is a video that accompain a peer-reviewed manuscript that provides detailed information on how to our affordable drug resistance testing. The paper and video are open accessible!


YouTube Video

Are subtype differences important in HIV drug resistance?

Author: Tulio de Oliveira - Date: 2013-10-10

Short interview about a review paper on HIV-1 subtypes and drug resistance


Open access pdf Publications

Sexual partnership age pairings and risk of HIV acquisition in rural South Africa.
Akulliana A, Bershteyna A, Kleina D, Vandormael A, Barnighausen T, Tanser F, AIDS (2017), :DOI:10.1097/QAD.0000000000001553.

Incidence rate estimation, periodic testing and the limitations of the mid-point imputation approach.
Vandormael A, Dobra A, Barnighausen T, de Oliveira T, Tanser F, International Journal of Epidemiology (2017), :doi.org/10.1093/ije/dyx134.

Mutational Correlates of Virological Failure in Individuals Receiving a WHO-Recommended Tenofovir-Containing First-Line Regimen: An International Collaboration.
Rhee SY, Varghese V, Holmes SP, Van Zyl GU, Steegen K, Boyd MA, Cooper DA, Nsanzimana S, Saravanan S, Charpentier C, de Oliveira T, Etiebet MA, Garcia F, Goedhals D, Gomes P, Gunthard HF, Hamers RL, Hoffmann CJ, Hunt G, Jiamsakul A, Kaleebu P, Kanki P, Kantor R, Kerschberger B, Marconi VC, D'amour Ndahimana J, Ndembi N, Ngo-Giang-Huong N, Rokx C, Santoro MM, Schapiro JM, Schmidt D, Seu L, Sigaloff KCE, Sirivichayakul S, Skhosana L, Sunpath H, Tang M, Yang C, Carmona S, Gupta RK, Shafer RW., EBioMedicine (2017), :doi: 10.1016/j.ebiom.2017.03.024.

High Rates of Transmission of Drug-resistant HIV in Aruba Resulting in Reduced Susceptibility to the WHO Recommended First-line Regimen in Nearly Half of Newly Diagnosed HIV-infected Patients.
Hofstra LM, Rivas ES, Nijhuis M, Bank LEA, Wilkinson E, Kelly K, Mudrikova T, Schuurman R, de Oliveira T, de Kort J, Wensing AMJ, Clinical Infectious Diseases (2017), :doi: 10.1093/cid/cix056.

Virological Outcomes of Second-line Protease Inhibitor-Based Treatment for Human Immunodeficiency Virus Type 1 in a High-Prevalence Rural South African Setting: A Competing-Risks Prospective Cohort Analysis.
Collier D, Iwuji C, Derache A, de Oliveira T, Okesola N, Calmy A, Dabis F, Pillay D, Gupta RK, for ANRS 12249 TasP Study Group, Clinical Infectious Diseases (2017), :doi: 10.1093/cid/cix015.

CD4+ T-cell count may not be a useful strategy to monitor antiretroviral therapy response in HTLV-1/HIV co-infected patients.
Vandormael A, Rego F, Danaviah S, Alcantara L, Boulware D, de Oliveira T, Current HIV Research (2017), :doi: 10.2174/1570162X15666170216114917.

Social disequilibrium and the risk of HIV acquisition: A multilevel study in rural KwaZulu-Natal Province, South Africa.
Tomita A, Vandormael AM, Barnighausen T, de Oliveira T, Tanser F, J Acquir Immune Defic Syndr. (2017), :10.1097/QAI.0000000000001349.

Sequence and Phylogenetic Analysis of the Untranslated Promoter Regions for HLA Class I Genes.
Ramsuran V, Hernandez-Sanchez PG, O'hUigin C, Sharma G, Spence N, Augusto DG, Gao X, Garcia-Sepulveda CA, Kaur G, Mehra NK, Carrington M,, J Immunol (2017), pii: 1601679:.

Primary HIV-1 Drug Resistant Minority Variants.
Chimukangara B, Samuel R, Naidoo K, de Oliveira T, AIDS Reviews (2017), 19(2):[Epub ahead of print].

Pairwise diversity and tMRCA as potential markers for HIV infection recency.
Moyo S, Wilkinson E, Vandormael A, Wang R, Weng J, Kotokwe KP, Gaseitsiwe S, Musonda R, Makhema J, Essex M, Engelbrecht S, de Oliveira T, Novitsky V , Medicine (Baltimore) (2017), 96:doi: 10.1097/MD.0000000000006041.

Sensitive next generation sequencing method reveals deep genetic diversity of HIV-1 in the Democratic Republic of the Congo.
Rodgers MA, Wilkerson E, Vallari A, McArthur C, Sthreshley L, Brennan CA, Cloherty G, de Oliveira T, Journal of Virology (2017), JVI.01841-16:doi: 10.1128/JVI.01841-16.

Complex subtype diversity of HIV-1 among drug users in major Kenyan cities.
Gounder K, Oyaro M, Padayachi N, Zulu TM,de Oliveira T, Wylie J, Ndung'u T, AIDS Res Hum Retroviruses (2017), :10.1089/AID.2016.0321.

Using nearly full-genome HIV sequence data improves phylogeny reconstruction in a simulated epidemic.
Yebra G, Hodcroft EB1, Ragonnet-Cronin ML1, Pillay D2, Brown AJ1; PANGEA_HIV Consortium de Oliveira T; ICONIC Project., Scientific Reports (2016), 6:39489. doi: 10.1038/srep39489.

HLA-C Level Is Regulated by a Polymorphic Oct1 Binding Site in the HLA-C Promoter Region.
Vince N, Li H, Ramsuran V, Naranbhai V, Duh FM, Fairfax BP, Saleh B, Knight JC, Anderson SK, Carrington M, Am J Hum Genet (2016), 99(6):1353-1358.

HIV drug resistance testing among patients failing second line antiretroviral therapy-Comparison of in-house and commercial sequencing.
Chimukangara B, Varyani B, Shamu T, Mutsvangwa J, Manasa J, White E, Chimbetete C, Luethy R, Katzenstein D, J Virol Methods (2016), pii: S0166-0934(16)30289-0: doi: 10.1016/j.jviromet.2016.11.010.

HTLV-1aA introduction into Brazil and its association with the trans-Atlantic slave trade.
Amoussa AE, Wilkinson E, Giovanetti M, de Almeida Rego FF, Araujo TH, de Souza Goncalves M, de Oliveira T, Alcantara LC, Infection, Genetics and Evolution (2016), 48:doi: 10.1016/j.meegid.2016.12.005.

Spread of yellow fever virus outbreak in Angola and the Democratic Republic of the Congo 2015-16: a modelling study.
Kraemer MUG, Faria NR, Reiner Jr RC, Golding N, Nikolay B, Stasse S, Johansson MA, Salje H, Faye O, Wint GRW, Niedrig M, Shearer FM, Hill SC, Thompson RN, Bisanzio D, Taveira N, Nax HH, Pradelski BSR, Nsoesie EO, Murphy NR, Bogoch II, Khan K, Brownstein JS, Tatem AJ, de Oliveira T, Smith DL, Sall AA, Pybus OG, Hay SI, Cauchemez S, Lancet Infectious Diseases (2016), http://dx.doi.org/10.1016/S1473-3099(16)30513-8:.

Occult HIV-1 drug resistance to thymidine analogues following failure of first-line tenofovir combined with a cytosine analogue and nevirapine or efavirenz in sub Saharan Africa: a retrospective multi-centre cohort study.
Gregson J, Kaleebu P, Marconi VC, van Vuuren C, Ndembi N, Hamers RL, Kanki P, Hoffmann CJ, Lockman S, Pillay D, de Oliveira T, Clumeck N, Hunt G, Kerschberger B, Shafer RW, Yang C, Raizes E, Kantor R, Gupta RK, Lancet Infectious Diseases (2016), pii: S1473-3099(16)30469-8:http://dx.doi.org/10.1016/S1473-3099(16)30447-9.

Transmission networks and risk of HIV infection in KwaZulu-Natal, South Africa: a community-wide phylogenetic study.
de Oliveira T, Kharsany ABM, Graf T, Cawood C, Khanyile D, Grobler A, Puren A, Madurai S, Baxter C, Karim QA, Karim SSA, Lancet HIV (2016), http://dx.doi.org/10.1016/S2352-3018(16)30186-2:.

Microbial genome-wide association studies: lessons from human GWAS.
Power RA, Parkhill J, de Oliveira T, Nature Reviews Genetics (2016), nrg.2016.132:doi:10.1038/nrg.2016.132.

Genome-Wide Association Study of HIV Whole Genome Sequences Validated using Drug Resistance.
Power RA, Davaniah S, Derache A, Wilkinson E, Tanser F, Gupta RK, Pillay D, de Oliveira T, PLoS One (2016), 11(9):e0163746.

Contribution of Gag and Protease to HIV-1 Phenotypic Drug Resistance in Pediatric Patients Failing Protease Inhibitor-Based Therapy.
Giandhari J, Basson AE, Sutherland K, Parry CM, Cane PA, Coovadia A, Kuhn L, Hunt G, Morris L, Antimicrob Agents Chemother. (2016), 60(4):2248-56.

Comprehensive Characterization of HIV-1 Molecular Epidemiology and Demographic History in the Brazilian Region Most Heavily Affected by AIDS.
Graf T, Fritsch HM, de Medeiros RM, Junqueira DM, Almeida SEM, Pinto AR , Journal of Virology (2016), 90(18):8160-8168.

Analysis of Viral Diversity in Relation to the Recency of HIV-1C Infection in Botswana.
Moyo S, Vandormael A, Wilkinson E, Engelbrecht S, Gaseitsiwe S, Kotokwe, KP, Musonda R, Tanser F, Essex M, Novitsky V, de Oliveira T, PLoS One (2016), 11(8):DOI:10.1371/journal.pone.0160649.

Relationship between HIV serostatus, CD4 count and rehospitalisation: Potential implications for health systems strengthening in South Africa.
Moodley Y, Tomita A, Southern African Journal of Infectious Diseases (2016), 1(1):1-6.

Substance use and duration of untreated psychosis in KwaZulu-Natal, South Africa.
Davis GP, Tomita A, Baumgartner JN, Mtshemla S, Nene S, King H, Susser E and Burns JK, South African Journal of Psychiatry (2016), 22(1):p. 7.

Origin, imports and exports of HIV-1 subtype C in South Africa: A historical perspective.
Wilkinson E, Rasmussen D, Ratmann O, Stadler T, Engelbrecht S, de Oliveira T, Infection, Genetics and Evolution (2016), S1567-1348(16)30298-2:doi: 10.1016/j.meegid.2016.07.008.

HIV drug resistance levels in adults failing first-line antiretroviral therapy in an urban and a rural setting in South Africa.
Rossouw TM, Nieuwoudt M, Manasa J, Malherbe G, Lessells RJ, Pillay S, Danaviah S, Mahasha P, van Dyk G, de Oliveira T, HIV Med. (2016), 2016 :doi: 10.1111/hiv.12400.

Zika virus complete genome from Salvador, Bahia, Brazil.
surname=de OliveiraGiovanetti M, Faria NR, Nunes MR, de Vasconcelos JM, Lourenco J, Rodrigues SG, Vianez JL Jr, da Silva SP, Lemos PS, Tavares FN, Martin DP, do Rosario MS, Siqueira IC, Ciccozzi M, Pybus OG, de Oliveira T, Alcantara LC Junior, Infection, Genetics and Evolution (2016), 41:142-145.

Improving HIV proteome annotation: new features of BioAfrica HIV Proteomics Resource .
Druce Megan, Hulo C, Masson P, Sommer P, Xenarios I, Le Mercier P, de Oliveira T, Database (2016), 2016:doi:10.1093/database/baw045.

Global epidemiology of drug resistance after failure of WHO recommended first-line regimens for adult HIV-1 infection: a multicentre retrospective cohort study.
The TenoRes Study Group* Gregson J, Tang M, Ndembi N, Hamers RL, ..., de Oliveira T, ..., Shafer RW, Gupta KR, Lancet Infect Dis. (2016), 15:http://dx.doi.org/10.1016/S1473-3099(15)00536-8.

Increasing HIV-1 drug resistance between 2010 and 2012 in adults participating in population-based HIV surveillance in rural KwaZulu-Natal South Africa.
Manasa J, Danaviah S, Lessells RJ, Elshareef M, Tanser F, Wilkinson E, Pillay S, Mthiyane H, Mwambi H, Pillay D, de Oliveira T, AIDS Res Hum Retroviruses (2016), 32(8):763-769.

The Development of Computational Biology in South Africa: Successes Achieved and Lessons Learnt.
Mulder NJ, Christoffels A, de Oliveira T, Gamieldien J, Hazelhurst S, Joubert F, Kumuthini J, Pillay CS, Snoep JL, Tastan Bishop O, Tiffin N, PLoS Comput Biol (2016), 12(2):e1004395.

Understanding Specific Contexts of Antiretroviral Therapy Adherence in Rural South Africa: A Thematic Analysis of Digital Stories from a Community with High HIV Prevalence.
Treffry-Goatley A, Lessells R, Sykes P, Barnighausen T, de Oliveira T, Moletsane R, Seeley J., PLoS One (2016), 11(2):doi: 10.1371/journal.pone.0148801.

Analysis of Dominant HIV Quasispecies Suggests Independent Viral Evolution Within Spinal Granulomas Coinfected with Mycobacterium tuberculosis and HIV-1 Subtype C.
Danaviah S, de Oliveira T, Gordon M, Govender S, Chelule P, Pillay S, Naicker T, Cassol S, Ndung'u T, AIDS Research and Human Retroviruses (2016), :doi:10.1089/aid.2015.0189.

Brief Report: Virologic Monitoring Can Be a Cost-Effective Strategy to Diagnose Treatment Failure on First-Line ART.
Vandormael AM, Boulware DR, Tanser FC, Barnighuasen TW, Stott KE, de Oliveira T, J Acquir Immune Defic Syndr. (2016), 71(4):462?466.

Deep Sequencing Analysis of Human T Cell Lymphotropic Virus Type 1 Long Terminal Repeat 5' Region from Patients with Tropical Spastic Paraparesis/Human T Cell Lymphotropic Virus Type 1-Associated Myelopathy and Asymptomatic Carriers..
Rego FF, de Oliveira T, Giovanetti M, Galvao-Castro B, Goncalves MS, Alcantara LC., AIDS Research and Human Retroviruses (2016), 32(3):279-83.

Epigenetic regulation of differential HLA-A allelic expression levels.
Ramsuran V, Kulkarni S, O'huigin C, Yuki Y, Augusto DG, Gao X, Carrington M, Hum Mol Genet (2015), 24(15):4268-75.

Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor.
Gornalusse GG, Mummidi S, Gaitan AA, Jimenez F, Ramsuran V, Picton A, Rogers K, Manoharan MS, Avadhanam N, Murthy KK, Martinez H, Molano Murillo A, Chykarenko ZA, Hutt R, Daskalakis D, Shostakovich-Koretskaya L, Abdool Karim S, Martin JN, Deeks SG, Hecht F, Sinclair E, Clark RA, Okulicz J, Valentine FT, Martinson N, Tiemessen CT, Ndung'u T, Hunt PW, He W, Ahuja SK., Proc Natl Acad Sci U S A (2015), 112(34):E4762-71.

Genetic Changes in HIV-1 Gag-Protease Associated with Protease Inhibitor-Based Therapy Failure in Pediatric Patients.
Giandhari J, Basson AE, Coovadia A, Kuhn L, Abrams AJ, Strehlau R, Morris L, Hunt GM, AIDS Res Hum Retroviruses (2015), 31(8):776-82.

Clinical, Virologic, Immunologic Outcomes and Emerging HIV Drug Resistance Patterns in Children and Adolescents in Public ART Care in Zimbabwe.
Makadzange AT, Higgins-Biddle M, Chimukangara B, Birri R, Gordon M, Mahlanza T, McHugh G, van Dijk JH, Bwakura-Dangarembizi M, Ndung'u T, Masimirembwa C, Phelps B, Amzel A, Ojikutu BO, Walker BD, Ndhlovu CE, PLoS One (2015), 10(12):DOI: 10.1371/journal.pone.0144057 .

History and origin of the HIV-1 subtype C epidemic in South Africa and the greater southern African region.
Wilkinson E, Engelbrecht S, de Oliveira T, Scientific Reports (2015), 5:16897. doi: 10.1038/srep16897.

HIV-1 Drug Resistance Mutations: Potential Applications for Point-of-Care Genotypic Resistance Testing.
Rhee SY, Jordan MR, Raizes E, Chua A, Parkin N, Kantor R, Van Zyl GU, Mukui I, Hosseinipour MC, Frenkel LM, Ndembi N, Hamers RL, Rinke de Wit TF, Wallis CL, Gupta RK, Fokam J, Zeh C, Schapiro JM, Carmona S, Katzenstein D, Tang M, Aghokeng AF, de Oliveira T, Wensing AM, Gallant JE, Wainberg MA, Richman DD, Fitzgibbon JE, Schito M, Bertagnolio S, Yang C, Shafer RW., PLoS One (2015), 10(12):e0145772. doi: 10.1371/journal.pone.0145772.

The Art of HIV Elimination: Past and Present Science.
Iwuji CC, McGrath N, de Oliveira T, Porter K, Pillay D, Fisher M, Newport M, Newell M-L, AIDS & Clinical Research (2015), 6: 525. doi:10.4172/2155-6113.1000525 .

Identifying Recent HIV Infections: From Serological Assays to Genomics.
Moyo S, Wilkinson E, Novitsky V, Vandormael A, Gaseitsiwe S, Essex M, Engelbrecht S, de Oliveira T , Viruses (2015), 7:5508-5524; doi:10.3390/v7102887.

Long-range HIV genotyping using viral RNA and proviral DNA for analysis of HIV drug-resistance and HIV clustering.
Novitsky V, Zahralban-Steele M, McLane MF, Moyo S, Widenfelt E, Gaseitsiwe S, Makhema J, Essex M, Journal of Clinical Microbiology (2015), in press:in press .

The origin of HTLV-1 in southern Bahia by phylogenetic, mtDNA and Beta-globin analysis.
Aleluia MM, Mello MAG,Alcantara LCJ, Rego FFA, Santos LPS, Galvao-Castro B, Goncalves MS, de Oliveira T, Marin LJ, Sousa SMB, Gadelha SR, Virology Reports (2015), :dx.doi.org/10.1016/j.virep.2015.05.002.

PANGEA-HIV: phylogenetics for generalised epidemics in Africa.
Pillay D, Herbeck J, Cohen MS, de Oliveira T, Fraser C, Ratmann O, Brown A-L, Kellam P, on behalf of the PANGEA-HIV Consortium, Lancet Infect Dis. (2015), 15(3):259-61.

Evidence of Long-Lived Founder Virus in Mother-to-Child HIV Transmission.
Danaviah S, de Oliveira T, Bland R, Viljoen J, Pillay S, Tuaillon E, Van de Perre P, Newell ML, PLoS One (2015), 10(3):e0120389.

Sequencing and phylogenetic analysis of near full-length HIV-1 subtypes A, B, G and unique recombinant AC and AD viral strains identified in South Africa.
Wilkinson E, Holzmayer V, Jacobs G, de Oliveira T, Brennan C, Hackett J Jr, Janse van Rensburg E, Engelbrecht S., AIDS Research and Human Retroviruses (2015), in press:.

Impact of drug resistance-associated amino acid changes in HIV-1 subtype C on susceptibility to newer nonnucleoside reverse transcriptase inhibitors.
Basson AE, Rhee SY, Parry CM, El-Khatib Z, Charalambous S, De Oliveira T, Pillay D, Hoffmann C, Katzenstein D, Shafer RW, Morris L, Antimicrob Agents Chemother (2015), pii: AAC.04215-14:pii: AAC.04215-14.

Expression of the CCR5 HIV co-receptor in women with genital schistosomiasis.
Kleppa E, Ramsuran V, Zulu S, Karlsen GH, Bere A, Passmore JA, Ndhlovu P, Lillebo K, Holmen SD, Onsrud M, Gundersen SG, Taylor M, Kjetland EF, Ndung'u T, 16th ICID Abstracts / International Journal of Inf (2014), 21S:1-460.

Effect of female genital schistosomiasis and anti-schistosomal treatment on monocytes, CD4+ T-cells and CCR5 expression in the female genital tract.
Kleppa E, Ramsuran V, Zulu S, Karlsen GH, Bere A, Passmore JA, Ndhlovu P, Lillebo K, Holmen SD, Onsrud M, Gundersen SG, Taylor M, Kjetland EF, Ndung'u T, PLoS One (2014), 9(6):e98593.

Use of antiretroviral therapy in households and risk of HIV acquisition in rural KwaZulu-Natal, South Africa, 2004-12: a prospective cohort study.
Vandormael A, Newell ML, Barnighausen T, Tanser F, Lancet Global Health (2014), 2:e209-215.

Drug resistance mutations from whole blood proviral DNA among patients on antiretroviral drugs in Zimbabwe.
Chimukangara B, Gwanzura G, Mitchell R, Katzenstein D, Masimirembwa C , Curr HIV Res (2014), 12(5):309-16.

Detection of Transmission Clusters of HIV-1 Subtype C over a 21-Year Period in Cape Town, South Africa.
Wilkinson E, Engelbrecht S, de Oliveira T, PLoS One (2014), 9(10):doi:10.1371/journal.pone.0109296.

HIV Drug Resistance Patterns at the Epicentre of the HIV-1 Epidemic in Kwazulu-Natal, South Africa 2003-2013.
Kiepiela P, Manasa J, Moosa M-Y, Moodley P, Gordon M, Parikh UM, Sunpath H, de Oliveira T, Ramjee G, J AIDS Clin Res (2014), 5:doi: 10.4172/2155-6113.1000299.

Phylogenetic studies of transmission dynamics in generalized HIV epidemics: An essential tool where the burden is greatest?.
Dennis AM, Herbeck JT, Brown AL, Kellam P, de Oliveira T, Pillay D, Fraser C, Cohen MS, J Acquir Immune Defic Syndr. (2014), in press:.

HIV-1 adaptation to antigen processing results in population-level immune evasion and affects subtype diversification.
Tenzer S, Crawford H, Pymm P, Gifford R, Sreenu VB, Weimershaus M, de Oliveira T, Burgevin A, Gerstoft J, Akkad N, Lunn D, Fugger L, Bell J, Schild H, van Endert P, Iversen AK., Cell Reports (2014), 7:doi: 10.1016/j.celrep.2014.03.031.

Circulating Biomarkers of Immune Activation Distinguish Viral Suppression from Nonsuppression in HAART-Treated Patients with Advanced HIV-1 Subtype C Infection.
Malherbe G, Steel HC, Cassol S, de Oliveira T, Seebregts CJ, Anderson R, Cassol E, Rossouw TM., Mediators Inflamm. (2014), 2014:198413:doi: 10.1155/2014/198413.

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings.
Manasa J, Danaviah S, Pillay S, Padayachee P, Mthiyane H, Seebregts C, Rinke De Wit TF, Viljoen J, Katzenstein D, De Oliveira T , Journal of Visualized Experiments (JoVE) (2014), (85):e51242, doi:10.3791/51242.

HIV-1 Subtypes B and C Unique Recombinant Forms (URFs) and Transmitted Drug Resistance Identified in the Western Cape Province, South Africa.
Jacobs GB, Wilkinson E, Isaacs S, Spies G, de Oliveira T, Seedat S, Engelbrecht S , PLoS One (2014), 9(3):e90845. doi:10.1371/journal.pone.0090845.

Implementing antiretroviral resistance testing in a primary health care HIV treatment programme in rural KwaZulu-Natal, South Africa: early experiences, achievements and challenges.
Lessells RJ, Stott KE, Manasa J, Naidu KK, Skingsley A, Rossouw T, de Oliveira T, BMC Health Services Research (2014), 14:116:doi:10.1186/1472-6963-14-116.

Southern African Treatment Resistance Network (SATuRN) RegaDB HIV drug resistance and clinical management database: supporting patient management, surveillance and research in southern Africa.
Manasa J, Lessells R, Rossouw T, Naidu K, Van Vuuren C, Goedhals D, van Zyl G, Bester A, Skingsley A, Stott K, de Oliveira T, Database (Oxford) (2014), Vol. 2014 :bat082. doi: 10.1093/database/bat082.

Drug resistance in children at virological failure in a rural KwaZulu-Natal, South Africa, cohort.
Pillay S, Bland RM, Lessells RJ, Manasa J, de Oliveira T, Danaviah S., AIDS Res Ther. (2014), 11(1):3. doi: 10.1186/1742-6405-11-3.

Concentrated HIV subepidemics in generalized epidemic settings.
Tanser F, de Oliveira T, Maheu-Giroux M, Barnighausen T, Curr Opin HIV AIDS (2014), 9(2):115-125.

Genetic interplay between HLA-C and MIR148A in HIV control and Crohn disease.
Kulkarni S, Qi Y, O'hUigin C, Pereyra F, Ramsuran V, McLaren P, Fellay J, Nelson G, Chen H, Liao W, Bass S, Apps R, Gao X, Yuki Y, Lied A, Ganesan A, Hunt PW, Deeks SG, Wolinsky S, Walker BD, Carrington M, Proc Natl Acad Sci U S A (2013), 110(51):20705-10.

Implementing HIV-1 Genotypic Resistance Testing in Antiretroviral Therapy Programs in Africa: Needs, Opportunities, and Challenges.
Lessells RJ, Avalos A, de Oliveira T, AIDS Reviews (2013), 15:221-229.

An Investigation of Classification Algorithms for Predicting HIV Drug Resistance without Genotype Resistance Testing.
Brandt P, Moodley D, Pillay AW, Seebregts CJ, de Oliveira T, Lecture Notes in Computer Science (LNCS) (2013), 8315:236-253.

A Pragmatic Approach to HIV-1 Drug Resistance Determination in Resource-Limited Settings by Use of a Novel Genotyping Assay Targeting the Reverse Transcriptase-Encoding Region Only.
Aitken SC, Bronze M, Wallis CL, Stuyver L, Steegen K, Balinda S, Kityo C, Stevens W, Rinke De Wit TF & Schuurman R., J Clin Microbiol (2013), 51:1757-1761.

Dramatic increases in HIV prevalence after scale-up of antiretroviral treatment: a longitudinal population-based HIV surveillance study in rural Kwazulu-Natal.
Zaidi J, Grapsa E, Tanser F, Newell M-L, Barnighausen T, AIDS (2013), 27(14):2301-2305.

High coverage of ART associated with decline in risk of HIV acquisition in rural KwaZulu-Natal, South Africa.
Tanser F, Barnighausen T, Grapsa E, Zaidi J, Newell M-L., Science (2013), 339(6122):966-971.

A qualitative and quantitative histopathological analysis of the host immune response to TB of the spine in HIV-positive and negative patients.
Danaviah S, Sacks J, Taylor L, Govender S, Fallows D, Kumar KPS, Ndung'u T, Kaplan G. , Tuberculosis (2013), 93(4):432-41.

Pili contribute to biofilm formation in vitro in Mycobacterium tuberculosis.
Ramsugit S, Guma S, Pillay B, Jain P, Larsen MH, Danaviah S, Pillay M., Antonie Van Leeuwenhoek (2013), 104(2):DOI 10.1007/s10482-013-9981-6.

Combined antiretroviral and antituberculosis drug resistance following incarceration.
Stott KE, de Oliveira T, Lessells RJ, S Afr J HIV Med (2013), 14(3):135-137.

Human Retrovirus Codon Usage from tRNA Point of View: Therapeutic Insights.
Frias D, Monteiro-Cunha JP, Mota-Miranda AC, Fonseca VS, de Oliveira T, Galvao-Castro B Alcantara LCJ, Bioinformatics and Biology Insights (2013), 7:1-11.

High-Levels of Acquired Drug Resistance in Adult Patients Failing First-Line Antiretroviral Therapy in a Rural HIV Treatment Programme in KwaZulu-Natal, South Africa.
Manasa J, Lessells RJ, Skingsley A, Naidu KK, Newell M-L, McGrath N, de Oliveira T, PLoS One (2013), 8(8):e72152.

High Level of HIV-2 False Positivity in KwaZulu-Natal Province: A Region of South Africa With a Very High HIV-1 Subtype C Prevalence.
Singh L, Parboosing R, Manasa J, Moodley P, de Oliveira T, Journal of Medical Virology (2013), Advanced Access:doi: 10.1002/jmv.23716.

Trends in Genotypic HIV-1 Antiretroviral Resistance between 2006 and 2012 in South African Patients Receiving First- and Second-Line Antiretroviral Treatment Regimens.
Van Zyl GU, Liu TF, Claassen M, Engelbrecht S, de Oliveira T, Preiser W, Wood NT, Travers S, Shafer RW, PLoS One (2013), 8(6):e67188.

Automated subtyping of HIV-1 genetic sequences for clinical and surveillance purposes: Performance evaluation of the new REGA version 3 and seven other tools.
Pena ACP, Faria NR, Imbrechts S, Libin P, Abecasis AB, Deforche K, Gomez A, Camacho RJ, de Oliveira T, Vandamme A-M, Infectious Genetics and Evolution (2013), in press :.

Development and evaluation of an affordable real-time qualitative assay for determining HIV-1 virological failure in plasma and dried blood spots..
Aitken SC, Kliphuis A, Bronze M, Wallis CL, Kityo C, Balinda S, Stevens WS, Spieker N, de Oliveira T, Rinke de Wit TF, Schuurman R., J Clin Microbiol (2013), 29 (11):JCM.03305-12.

RegaDB: Community-driven data management and analysis for infectious diseases.
Libin P, Beheydt G, Deforche K, Imbrechts S, Ferreira F, Van Laethem K, Theys K, Carvalho AP, Cavaco Silva J, Lapadula G, Torti P, Assel M, Wesner S, Snoeck J, Ruelle J, De Bel A, Lacor P, De Munter P, Van Wijngaerden E, Zazzi M, Kaiser R, Ayouba A, Peeters M, de Oliveira T, Alcantara L, Grossman Z, Sloot P, Otelea D, Paraschiv S, Boucher C, Camacho R, and Vandamme AM, Bioinformatics (2013), 29 (11):1477-1480, doi: 10.1093/bioinformatics/btst162 .

HIV & TB Drug Resistance & Clinical Management Case Book.
Rossouw T, Lessells RJ, de Oliveira T, South African Medical Research Council Press (2013), ISBN 978-1-920014-91-9:.

Searching for Virus Phylotypes.
surname=de OliveiraChevenet F, Jung M, Peeters M, de Oliveira T, Gascuel O, Bioinformatics (2013), 29 (5):561-570.

Universal Amplification, Next-Generation Sequencing, and Assembly of HIV-1 Genomes.
Gall A, Ferns B, Morris C, Watson S, Cotten M, Robinson M, Berry N, Pillay D, Kellam P, Journal of Clinical Microbiology (2012), 50(12):doi:10.1128/JCM.01516-12.

In-house human immunodeficiency virus-1 genotype resistance testing to determine highly active antiretroviral therapy resistance mutations in Hong Kong.
Chen JH, Wong KH, Li PC, Chan KK, Lee MP, To SW, Yam WC , Hong Kong Med J (2012), 18:20-24.

Principles of HIV drug resistance for clinical management in South Africa.
Stott K, Michel J, de Oliveira T, HIV Nursing Matters (2012), 3(4):46-51.

The 2012 southern African ARV drug resistance testing guidelines.
Conradie F, Wilson D, Basson A, de Oliveira T, Hunt G, Joel D, Papathanasopoulos M, Preiser W, Klausner J, Spencer D, Stevens W, Venter F, van Vuuren C, S Afr J HIV Med (2012), 13(4):162-167.

Are subtype differences important in HIV drug resistance?.
Lessells RJ, Katzenstein DK, de Oliveira T, Current Opinion Virology (2012), 2(5):636-43.

Gender Differences in Survival among Adult Patients Starting Antiretroviral Therapy in South Africa: A Multicentre Cohort Study.
Cornell M, Schomaker M, Garone DB, Giddy J, Hoffmann CJ, Lessells R, Maskew M, Prozesky H, Wood R, Johnson LF, Egger M, Boulle A, Myer L For IeDEA-SA, PLoS Medicine (2012), 9(9):e1001304.

The tainted milk of human kindness.
Goedhals D, Rossouw I, Hallbauer U, Mamabolo M, de Oliveira T, Lancet (2012), 380:702.

WHO HIV drug resistance report 2012.
WHO ResNet, including - Jordan MR, Barcarolo J, Parkin N, de Oliveira T (analysis support), Bertagnolio S, WHO report (2012), ISBN 978 92 4 150393 8:.

Modeling HIV-1 Drug Resistance as Episodic Directional Selection.
Murrell B, de Oliveira T, Seebregts C, Kosakovsky-Pond SL, Scheffler K, on behalf SATuRN, PLoS Comput Biol (2012), 8(5):e1002507.

Primary drug resistance in South Africa - data from 10 years of surveys.
Manasa J, Katzenstein D, Cassol S, Newell ML, de Oliveira T, AIDS Res Hum Retroviruses (2012), 28(6):558-565.

Influence of variations in CCL3L1 and CCR5 on tuberculosis in a northwestern Colombian population.
Mamtani M, Mummidi S, Ramsuran V, Pham MH, Maldonado R, Begum K, Valera MS, Sanchez R, Castiblanco J, Kulkarni H, Ndung'u T, He W, Anaya JM, Ahuja SK, J Infect Dis (2011), 203(11):1590-4.

Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women.
Ramsuran V, Kulkarni H, He W, Mlisana K, Wright EJ, Werner L, Castiblanco J, Dhanda R, Le T, Dolan MJ, Guan W, Weiss RA, Clark RA, Karim SS, Ahuja SK, Ndung'u T, Clin Infect Dis. (2011), 52(10):1248-56.

Optimization of a low cost and broadly sensitive genotyping assay for HIV-1 drug resistance surveillance and monitoring in resource-limited settings..
Zhou Z, Wagar N, Devos JR, Rottinghaus E, Diallo K, Nguyen DB, Bassey O, Ugbena R, Wadonda-Kabondo N, Mcconnell MS, Zulu I, Chilima B, Nkengasong J, Yang C , PLoS One (2011), 6:e28184.

Cumulative exposure to cell-free HIV in breast milk, rather than feeding pattern per se, identifies postnatally infected infants.
Neveu D, Viljoen J, Bland RM, Nagot N, Danaviah S, Coutsoudis A, Rollins NC, Coovadia HM, Van de Perre P, Newell ML. , Clin Infect Dis (2011), 52(6):819-25.

Use of dried blood spots for the determination of genetic variation of IL-10, Killer Immunoglobulin-like Receptor and HLA Class I genes.
Ndlovu BG, Danaviah S, Moodley E, Ghebremichael M, Bland R, Viljoen J, Newell M-L, Ndung'u T, and Carr WH, Tissue Antigens (2011), 79(2):114-22.

Surveillance of transmitted antiretroviral drug resistance among HIV-1 infected women attending antenatal clinics in Chitungwiza, Zimbabwe..
Tshabalala M, Manasa J, Zijenah LS, Rusakaniko S, Kadzirange G, Mucheche M, Kassaye S, Johnston E, Katzenstein D, PLoS ONE (2011), 6(6):e21241.

KRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websitesKRISP Blogs from Bioafrica and SATuRN websites
Blogs Blogs Description & Link

KRISP Blogs from Bioafrica and SATuRN websites

Bioinformaticians are pioneering the future of science

Author: Yumna Moosa - 2017-07-28

Meeting of the Swiss, Swedes and South Africans minds

Author: Nicolette Crozier, Benjamin Chimukangara, Veron Ramsuran - 2017-07-25

Megan Druce: from Cum Laude MSc to a Scholarship for a PhD in Germany...

Author: Megan Druce - 2016-04-18

Sthembiso Msweli: from Hlabisa to MSc and Further Promoted to Laboratory Manager...

Author: Sthembiso Msweli - 2016-04-17

Experience of 3 UKZN/Africa Centre students at the 7-week national bioinformatics workshop 2015

Author: Megan Druce, Zandile Sibisi & Sthembiso Msweli - 2015-04-23

Tale of 4 Cities in outlining researcher's strive towards a cure for HIV

Author: Siva Danaviah - 2014-10-14

Massive Open Online Courses: Huge potential for bioinformatics education

Author: Rachael Dellar - 2014-10-13

First impressions of a South African student working in Geneva as part of Swiss South Africa Joint Research Programme (SSAJRP)

Author: Megan Druce - 2014-10-07

HIV, TB and Malaria Molecular Diagnostics Workshop, Harare, Zimbabwe 2014

Author: Justen Manasa - 2014-10-06

Genetic study indicates two novel resistance loci for severe malaria in Africa

Author: Zakia Jeewa and Tulio de Oliveira - 2014-08-01

High-Level Cross-Resistance to ddI Observed in South African Children Failing an ABC- or d4T-Based 1st-Line Regimen

Author: Jennifer Giandhari and Joanna Ledwaba - 2014-07-25

The fidelity of HIV-1 RT is not as bad as we thought

Author: Adriaan E. Basson - 2014-07-24

Report on Policy Meeting on HIV Drug Resistance, 6 May 2014, Lusaka, Zambia

Author: Jose IJedema, Sonia Boender & Tobias Rinke de Wit on behalf of PASER - 2014-07-05

Wellcome Trust Africa Centre Seminar & Twitter Q&A on HIV drug resistance in Africa, 15-Jan-2014

Author: Tulio de Oliveira - 2014-01-16

Multi-step inhibition explains HIV-1 protease inhibitor pharmacodynamics and resistance

Author: Jennifer Giandhari - 2013-10-10

Simultaneous detection of major HIV-1 drug resistance mutations using a multiplex allele-specific assay

Author: Anna Salimo - 2013-09-25

VideoBlog: SATuRN-PASER Scientific Meeting on HIV Drug Resistance in Africa

Author: Sonia Boender - 2013-09-20

Unresolved non-adherence drives early 2nd line ART failure

Author: Christopher Hoffmann - 2013-08-23

Data Curation and its tenets

Author: Lungani Ndwandwe, Tulio de Oliveira - 2013-08-15

South African scientific excellence: South African AIDS scientist to lead UNAIDS Expert Panel

Author: Tulio de Oliveira - 2013-07-01

Pirate Science - an interesting website on open-access phylogenetic publications

Author: Tulio de Oliveira - 2013-04-28

The Mississippi baby? questions on a 'functional' cure

Author: Gillian Hunt, Nono Mkhize, Mark Cotton - 2013-04-10

SATuRN on the Chair of African Dreams

Author: Lungani Ndwandwe, Justen Manasa, Xolile Kineri, Zakhona Gumede, Astrid Treffry-Goatley, Eduan Wilkinson, Tulio de Oliveira - 2013-04-06

Extensively drug-resistant tuberculosis in South Africa: are we now dealing with untreatable strains?

Author: Richard Lessells - 2013-02-22

The search for a new TB vaccine - a step forward or backward?

Author: Richard Lessells - 2013-02-21

Internet Freedom Activist Commit Suicide due to Criminal Charges for Distributing Academic Publications. We Increase the Open Distribution of our Publications!

Author: Tulio de Oliveira - 2013-01-15

The Southern African Treatment Resistance Network (SATuRN) at the KZNSA Gallery

Author: Lungani Ndwandwe, Tulio de Oliveira - 2012-12-01

It's all about the process - A doctor and LSHTM MSc student experiences at Africa Centre/SATuRN

Author: Dr. Baljinder Singh - 2012-10-01

Zooming in on home-based health care givers in rural South Africa

Author: Lungani Ndwandwe, Tulio de Oliveira - 2012-09-13

AIDS XIX 2012 conference: impressions of a South African researcher

Author: Siva Danaviah - 2012-09-12

Capturing Health in one Photo: a personal reflection

Author: Lungani Ndwandwe and Astrid Treffry-Goatley - 2012-08-14

ACiLT Practical Course on Quality Assurance of HIV-1 Drug Resistance Interpretation in Sequence Editing and Data Management Process, 7-11 May 2012

Author: Justen Manasa, Tulio de Oliveira - 2012-06-01

National Strategic Plan 2012-2016: Integrating research and all sectors of society to fight HIV, STIs and TB in South Africa

Author: Lungani Ndwandwe, Tulio de Oliveira - 2012-04-20

Shortage of doctors in rural South Africa?

Author: Lungani Ndwandwe, Tulio de Oliveira - 2012-03-29

More follow-up data on phase 2 trial of bedaquiline (TMC-207)

Author: Richard Lessells - 2012-03-15

Poetry: Toward A SATuRN Hope

Author: Joshua Machao - 2012-03-14

Drug resistance in Mycobacterium tuberculosis: do sputum specimens tell us everything?

Author: Richard Lessells - 2012-03-14

Social Worker perspective: Adolescents on Antiretroviral (ARV) therapy - a VideoBlog

Author: Pretty Nkosi, Nokuthula Skhosana, Lungani Ndwandwe and Tulio de Oliveira - 2012-02-10

Drug-resistant tuberculosis in Swaziland: a concern for us all

Author: Richard Lessells - 2012-01-24

'Totally drug-resistant' tuberculosis in India: should we be worried?

Author: Richard Lessells - 2012-01-23

Scientific Community Engagement Activities in rural KwaZulu-Natal, South Africa

Author: Tulio de Oliveira - 2012-01-22

Botswana hosted a successful HIV and TB workshop

Author: Tulio de Oliveira, Lungani Ndwandwe - 2011-12-01

Blogging from the Field: SATuRN Workshop in Gaborone

Author: Alisson Russell - 2011-11-02

Jiving with Science - an effective way of engaging the public

Author: Astrid Treffry-Goatley - 2011-06-12

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News News Description and Link

KRISP News Section from Bioafrica and SATuRN websites

KRISP Training

11th Annual Workshop on Advanced Clinical Care - AIDS (AWACC), Durban, South Africa, 6-7 Sep 2017

KRISP Training - 2017-10-06

The workshop is targeted at 400 clinicians, clinical virologists and nurses working in the public sector who are currently involved in the treatment of patients with HIV and TB in KwaZulu-Natal, South Africa.


KRISP Training

X-meeting - 13th International Conference of the AB3C, Sao Pedro, Brazil, Oct 4-6, 2017

KRISP Training - 2017-09-04

Bioinformatics is now a strategic area for Brazil and all Latin America and, therefore, it is also strategic to the development of Science, Technology and Economy. The X-Meeting is a Brazilian event with international reach which has an average of 400 participants.


KRISP Training

22nd International Bioinformatics Workshop on Virus Evolution and Molecular Epidemiology (VEME), Lisbon, Portugal

KRISP Training - 2017-08-27

The workshop provides both theoretical and practical training in phylogenetic inference and evolutionary hypothesis testing. It is recognized as one of the best international virus bioinformatics courses. It covers sequence analysis, phylogenetics, phylodynamics methods and large scale methods for next-generation sequencing (NGS) analytics


KRISP Talks

A multi-centre analysis of internal migration and AIDS/TB and NCD-related mortality in Kenya and South Africa

KRISP Talks - 2017-08-23

KRISP Talks by Dr Carren Ginsburg, SAMRC/Wits Rural Public Health & Health Transitions Research Unit (Agincourt), 23 August 2017 (11am - midday), K-RITH building, Nelson R Mandela School of Medicine, UKZN, Durban, South Africa. All welcome!


KRISP Newsletter

KRISP Newsletter - July 2017: news, videos, blogs, publications and training events

KRISP Newsletter - 2017-08-01

The concept behind this newsletter is that anyone with 15 minutes to spare can learn about KRISP work. In this July 2017 issue of our newsletter, we have included interesting news, videos, blogs, reports, tweets, publications and training events of KRISP


KRISP News

State-of-art lab for DNA sequencing a boost for KZN

KRISP News - 2017-07-30

By Siboniso Mngadi, Sunday Tribune. WITH a new, state-of-the-art laboratory at the University of KwaZulu-Natal's (UKZN) medical school, Durban can now produce some of the best, high-quality data in DNA sequencing without having to send it out of the province or to other countries.


KRISP News

Enabling Infectious Disease Transmission Research

KRISP News - 2017-07-27

KRISP Researcher and Fulbright scholar Dr. Eduan Wilkinson news from the US: HiPerGator supercomputer is enabling infectious disease transmission research in UF's Emerging Pathogens Institute.


KRISP News

KRISP & SANTHE trainee wins Best Abstract at DELTAS Africa meeting

KRISP News - 2017-07-20

Friday, 7 July, 2017, Dr Marcel Tongo Passo, a SANTHE Post-doctoral trainee, has won a "Best Abstract" award at the DELTAS (Developing Excellence in Leadership, Training and Science) Africa Annual Grantees Meeting 2017, held in Accra, Ghana, between 3 to 5 July. Passo is based at KRISP (KwaZulu-Natal Research and Innovation Sequencing Platform) and HPP (HIV Pathogenesis Programme) at the University of KwaZulu-Natal, South Africa.


KRISP News

Durban at the forefront of DNA research - KwaZulu-Natal Research and Innovation Sequencing Platform - KRISP

KRISP News - 2017-07-15

By Arthi Gopi, Independent on Saturday Newspaper - KRISP atrracts the brightest - Durban is leading the way in DNA research, having attracted some of the brightest minds in the science field, in a new state-of-the-art lab in the city.


KRISP News

KwaZulu-Natal Research and Innovation Sequencing Platform (KRISP) Established

KRISP News - 2017-07-12

The Technology Innovation Agency (TIA) and UKZN have signed an agreement for the establishment of KRISP - the KwaZulu-Natal Research and Innovation Sequencing Platform.


KRISP Talks

Seminar: Can the type of jeans you wear determine your treatment response?

KRISP Talks - 2017-06-23

KRISP Talks by Professor Bonga Chiliza, Discipline of Psychiatry: College of Health Sciences, UKZN, 23 June 2017, K-RITH building, Nelson R Mandela School of Medicine, Durban, South Africa. All welcome!


KRISP Newsletter

Newsletter, Jan-Mar 2017: 'Alarming' drug resistance levels, novel next generation sequencing method and the origin of HIV, SATuRN & CAPRISA workshop

KRISP Newsletter - 2017-03-31

The concept behind this newsletter is that anyone with 15 minutes to spare can learn about our research work. In this Jan-Mar 2017 issue of our newsletter, we have included interesting open access publications, news, blogs, reports, tweets, and training information produced by our group.


KRISP & CAPRISA

KRISP/SATuRN & CAPRISA 2017: HIV & TB Drug Resistance and Advanced Care Workshop

KRISP & CAPRISA - 2017-03-30

The workshop is targeted at clinicians, clinical virologists and nurses working in the public sector who are currently involved in the treatment of patients with HIV and TB in KwaZulu-Natal, South Africa.


IDSE Infectious Diseases

CD4+ Count Not Useful to Assess ART Response in HTLV-1/HIV Coinfection

IDSE Infectious Diseases - 2017-03-21

Patients coinfected with human T-cell lymphotropic virus 1 (HTLV-1) and HIV continue to have elevated CD4+ T-cell counts, even though there is no difference in their HIV viral load levels after antiretroviral therapy when compared with patients who just have HIV (Curr HIV Res 2017).


KRISP Talks

Seminar: Microbial genome-wide association studies: lessons from human GWAS

KRISP Talks - 2017-03-17

KRISP Talks by Prof. Tulio de Oliveira, College of Health Sciences, UKZN & CAPRISA Research Associate, 17 March 2017, K-RITH building, Nelson R Mandela School of Medicine, Durban, South Africa


Healio News

Prevalence of drug-resistant HIV reaches 'alarming levels' in Aruba

Healio News - 2017-03-17

The prevalence of resistance to nonnucleoside reverse transcriptase inhibitors among HIV-infected individuals has increased to 'alarming levels' in Aruba, reaching 45% in 2015, see our recent publication at CID.


Healio News: IAS Perspective

Perspective: Extreme high-level of drug resistance in Aruba: We need ITI-based regimens available globally now!

Healio News: IAS Perspective - 2017-03-17

Perspective by Carlos del Rio, MD Professor of medicine, division of infectious diseases, Emory University School of Medicine on our recent CID manuscript on high-level transmitted resistance epidemic in Aruba.


EurekaAlert!

CD4+ T-cell count useful to assess antiretroviral therapy response in HTLV-1/HIV patients?

EurekaAlert! - 2017-03-17

News coverage and clinical management implication of our recent HIV/HTLV co-infection manuscript, Current HIV Research, 2017


SANTHE

We have been awarded a collaborative grant from SANTHE/Wellcome Trust programme in Africa

SANTHE - 2017-02-28

The Wellcome Trust DELTAS funded SANTHE program awarded seven grants to develop collaborative research projects to address critical challenges to African capacity in HIV and/or TB clinical, social/behavioural, and biomedical science.


Swiss National Science Foundation & SA NRF

Swiss South African Symposium on Pathogen Genomics

Swiss National Science Foundation & SA NRF - 2017-02-23

The National Research Foundation and Swiss National Science Foundation through their Swiss-South Africa programme, have funded a project entitled: A context-based knowledge resource integrating HIV and Mtb molecular biology with host-pathogen and drug-resistance data. As part of the project, the University of Cape Town Computational Biology Division and our research group at UKZN are hosting a symposium on pathogen genomics.


KRISP Talks

Seminar: Differential HLA-A Expression Levels and the Effect on HIV

KRISP Talks - 2017-01-27

KRISP Talks by Dr Veron Ramsuran, Senior Lecturer: College of Health Sciences, UKZN, 27 January 2017, K-RITH building, Nelson R Mandela School of Medicine, Durban, South Africa


BioAfrica & SATuRN

Newsletter, Dec 2016: Ethics & phylogenetics, HIV transmission cycle, UNAIDS Report, Drug resistance increases in Africa

BioAfrica & SATuRN - 2016-12-15

The concept behind this newsletter is that anyone with 15 minutes to spare can learn about our research work. In this December 2016 issue of our newsletter, we have included interesting news, blogs, reports, tweets, publications and training information produced by our group.


Nelson Mandela School of Medicine, UKZN

Ethics and Viral Genomics: An Exploration of Ethical Issues Associated with HIV Phylogenetics

Nelson Mandela School of Medicine, UKZN - 2016-12-09

This is a half-day interactive workshop, which seeks to explore and deliberate on key ethical issues associated with HIV phylogenetic analysis as applied in our understanding of HIV transmission dynamics, particularly in African settings. Keynote presentations will be followed by plenary discussions led by the speakers.


The Lancet Infectious Diseases

Time to get serious with HIV-1 resistance in sub-Saharan Africa

The Lancet Infectious Diseases - 2016-12-02

In The Lancet Infectious Diseases, John Gregson and colleagues report the results of a meta-analysis investigating HIV-1 drug resistance in 20 studies from sub-Saharan Africa.


Mercury

Unrelenting spread of HIV amongst Adolescent girls and young women in rural and urban KwaZulu-Natal

Mercury - 2016-12-01

By Professor Ayesha Kharsany, December 1, 2016, Durban - Globally, over 1.6 billion people are in the age group 12-24 years, the largest generation of adolescents and young people. However, almost 42% of new HIV infections occur in this age group, nearly 80% of these live in sub-Saharan Africa and more than 70% of these infections occur in adolescent girls and young women. Not only do these adolescent girls and young women have higher rates of HIV, they also acquire infection 5-7 years earlier than their male peers.


The Lancet

Two manuscripts featured in the Lancet website front webpage on AIDS day.

The Lancet - 2016-12-01

Two of our recently published manuscripts (de Oliveira et al. Lancet HIV 2016 & Gregson et al Lancet Infectious Diseases 2016) are highlighed in the Lancet website front webpage...


UNAIDS

UNAIDS Report 2016 - Get on the Fast-Track - The life-cycle approach to HIV

UNAIDS - 2016-11-22

In this report, UNAIDS is announcing that 18.2 million people now have access to HIV treatment. The Fast-Track response is working. Increasing treatment coverage is reducing AIDS-related deaths among adults and children. But the life-cycle approach, which highlight our phylogenetics manuscript (de Oliveira et al. Lancet HIV 2016), has to include more than just treatment.


Reuters

More than 18 million on HIV treatment, a million more than 2015: UNAIDS 2016 Report

Reuters - 2016-11-22

More than 18 million people now have access to life-saving AIDS treatment, 1.2 million more than at the end of last year, the United Nations said on Monday. With detailed data showing some of the many complexities of the HIV epidemic, the report found that people are particularly vulnerable to HIV at certain points in their lives (de Oliveira et al. Lancet HIV 2016). It called for 'life-cycle; approach to offer help and prevention measures for everyone at every stage of life.


AWACC

10th Annual Workshop on Advanced Clinical Care - AIDS (AWACC)

AWACC - 2016-10-06

This AWACC annual workshop is in the 10th edition and it is organized as a joint effort of the Centre for AIDS research (CFAR) of Harvard Medical School, SATuRN, CAPRISA, UKZN and the KwaZulu-Natal Department of Health. AWACC objecitve is to translate the latest evidence-based research and apply best practice models of care into good clinical practice, specifically for resource constrained areas.


SATuRN

SATuRN Newsletter, 3rd quarter, 2016: SATuRN/CAPRISA, Rural vs Urban resistance levels, PhD fellowships, AWACC workshop

SATuRN - 2016-10-01

The concept behind this newsletter is that anyone with 15 minutes to spare can learn about the work of SATuRN. In this third 2016 issue of our newsletter we have included interesting news, blogs, reports, tweets, publications and training information produced by our network. We hope you enjoy it and find it informative. We welcome any feedback about content or format.


SASBi & SAGS

4th Joint Congress of the South African Society for Bioinformatics (SASBi) and the South African Genetics Society (SAGS)

SASBi & SAGS - 2016-09-23

The biennial SASBi and SAGS congresses are the premier national scientific meetings on bioinformatics and genetics in South Africa. In total, 187 participats delivered 40 oral presentations and 65 posters in SASBi-SAGS-2016. This congress provided an exciting opportunity to learn about cutting-edge research in both disciplines, and to network with members of the two societies and with leading international scientists.


CAPRISA, UKZN & MRC Flagship

PhD Fellowships: 2x postions at CAPRISA on Genomics, Bioinformatics, HIV-1 Drug resistance and/or Phylogenetics

CAPRISA, UKZN & MRC Flagship - 2016-08-24

The Professional Development Programme (PDP) of the Department of Science and Technology (DST) and the National Research Foundation (NRF) at CAPRISA aims to develop and retain South African scientists and professionals of the highest calibre.


CAPRISA, UKZN & MRC Flagship

PhD Fellowship I: Genomics, Bioinformatics & Drug Resistance

CAPRISA, UKZN & MRC Flagship - 2016-08-23

The Professional Development Programme (PDP) at CAPRISA aims to develop and retain South African scientists and professionals of the highest calibre. The genomics and bioinformatics project in HIV-1 drug resistance is inter-disciplinary in nature and involves collaboration between the CAPRISA's MRC HIV-TB Pathogenesis and Treatment Research Unit and the Flagship Program of the MRC, which are two of the most prestigious research programs in South Africa.


CAPRISA, UKZN & MRC Flagship

PhD Fellowship II: Genomics, Bioinformatics, Epidemioloy and Phylogenetics

CAPRISA, UKZN & MRC Flagship - 2016-08-23

The Professional Development Programme (PDP) at CAPRISA aims to develop and retain South African scientists and professionals of the highest calibre. The genomics and bioinformatics project in HIV-1 phylogenetics and molecular epidemiology is inter-disciplinary in nature and involves collaboration between the CAPRISA's MRC HIV-TB Pathogenesis and Treatment Research Unit and the Flagship Program of the MRC, which are two of the most prestigious research programs in South Africa.


Nature

Social cycle aids HIV spread

Nature - 2016-07-21

Nature (Vol. 535, pp. 335, 2016) report our recent results on the use of genetic sequences to uncover HIV-1 transmission patterns in young woman in South Africa (de Oliveira et al. Lancet HIV 2016). The paper was presented as a Keynote at AIDS 2016 conference.


Wall Street Journal

Studies Offer Fresh Hope in Fight Against HIV/AIDS in South Africa.

Wall Street Journal - 2016-07-18

Researchers with the Centre for the AIDS Programme of Research in South Africa, or CAPRISA, a consortium of South African and North American scientists, analyzed genetic codes (de Oliveira et al. Lancet HIV 2016) from study subjects in South Africa to try to pinpoint biological factors that may contribute, along with behavioral factors, to the large number of infections.


Science

South Africa's bid to end AIDS

Science - 2016-06-29

Science magazine (Vol. 353, Issue 6294, pp. 18-21, 2016). This issue was published before the AIDS conference in Durban 2016 and highlights some of our research, including our treatment as prevention trial (TasP) as well our phylogenetic analysis (de Oliveira et al. Lancet HIV 2016).


UKZN MRC Flagship

First two South African MSc students graduate from the MRC Flagship Program: Inspiring blogs about their experiences and achievements

UKZN MRC Flagship - 2016-04-15

Megan Druce and Sthembiso Msweli are two very bright South Africans who have successfully completed their MSc as part of the UKZN Flagship program at the MRC. They both wrote inspiring blogs, the first is about a Cum Laude degree which allowed the award of a scholarship for a PhD in Germany, the second is about the history of a laboratory technologist from rural KZN, who after graduating was promoted to laboratory manager...


SATuRN

SATuRN Newsletter, 2016: SATuRN/CAPRISA, Increase transmitted resistance, TDF global resistance

SATuRN - 2016-04-01

The concept behind this newsletter is that anyone with 15 minutes to spare can learn about the work of SATuRN. In this first 2016 issue of our newsletter we have included interesting news, blogs, reports, tweets, publications and training information produced by our network. We hope you enjoy it and find it informative. We welcome any feedback about content or format.


Rega Institute & Korea University College of Medicine

21st International Bioinformatics Workshop on Virus Evolution and Molecular Epidemiology (VEME)

Rega Institute & Korea University College of Medicine - 2016-03-15

The 21st International Workshop on Virus Evolution and Molecular Epidemiology (VEME2016) will be hosted by the Korea University College of Medicine, 14-19 August, Seoul, Republic of Korea. Abstract deadline: 15 March 2016


KRISP Talks

Seminar: A phylodynamic view of the HIV epidemic in KwaZulu-Natal

KRISP Talks - 2016-03-11

KRISP Talks by Dr David Rasmussen, Postdoc Research Fellow, ETH Zurich, 11 March 2016, K-RITH building, Nelson R Mandela School of Medicine, Durban, South Africa


KRISP Talks

Seminar: Sources of HIV infection among men having sex with men and implications for prevention

KRISP Talks - 2016-02-05

KRISP Talks by Oliver Ratmann, Research Fellow, Department Infectious Disease Epidemiology, Imperial College of London & UKZN MRC Research Fellow, 06 February 2016, K-RITH building, Nelson R Mandela School of Medicine, Durban, South Africa


SATuRN & AWACC

SATuRN & AWACC workshop - 19-20 November 2015, Durban, South Africa

SATuRN & AWACC - 2015-11-19

The SATuRN 10th Southern African HIV & TB Drug Resistance and Treatment Monitoring Workshop will be run together with the Annual Workshop on Advanced Clinical Care - AIDS (AWACC) - Durban, South Africa, 19 to 20 November 2015


Africa Centre

Positions open! Bioinformatics Software Developer & Scientific Manager

Africa Centre - 2015-09-15

Africa Centre through its European Commission Virogenesis Project & MRC Flagship Programmer wish to recruit a 1) Software Developer & 2) Bioinformatics Scientific Manager.


KRISP Talks

Seminar: Is HIV-1 subtype C more pathogenic than other subtypes?

KRISP Talks - 2015-08-21

We cordially invites you to a seminar presented by Prof Thumbi Ndungu from K-RITH and HPP/UKZN, 21 August 2015, K-RITH building, Nelson R Mandela School of Medicine, Durban, South Africa


WTAC & MRC Flagship UKZN

Research travel grants: Doctoral or post-doctoral students to Wellcome Trust Africa Centre, South Africa

WTAC & MRC Flagship UKZN - 2015-08-15

Introduction: This is an excellent opportunity for outstanding and motivated individuals to access one of the most comprehensive population-based HIV surveillance and genomics datasets in the world at the Wellcome Trust Africa Centre for Health and Population Studies based in KwaZulu-Natal, South Africa.


KRISP Talks

Seminar: The Molecular Epidemiology of HIV in Rakai Uganda

KRISP Talks - 2015-07-17

The Wellcome Trust Africa Centre Genomics & Bioinformatics Programme & UKZN MRC Flagship project cordially invites you to a seminar presented by Prof. Oliver Laeyendecker Assistant Professor of Medicine, Johns Hopkins University,19 June 2015, K-RITH building, Nelson R Mandela School of Medicine, Durban, South Africa


KRISP Talks

Seminar: Clinical Impressions of HIV Pathogenesis & Vaccine Research

KRISP Talks - 2015-06-19

The Wellcome Trust Africa Centre Genomics & Bioinformatics Programme & UKZN MRC Flagship project cordially invites you to a seminar presented by Dr Nigel Garrett from CAPRISA, 19 June 2015, K-RITH building, Nelson R Mandela School of Medicine, Durban, South Africa


Science

MOLECULAR EPIDEMIOLOGY: HIV family trees reveal viral spread.

Science - 2015-06-12

By John Cohen, Science, 12 June 2015. New studies could aid public health efforts. Last week at the New York Academy of Sciences in New York City, researchers, public health specialists, and HIV/AIDS advocates discussed how to exploit the potential of the technique, called phylogenetic analysis - and the thorny ethical and legal issues it raises...


UNAIDS

Feature story: Understanding HIV through phylogenetic research

UNAIDS - 2015-06-08

Phylogenetic research 'the analysis of molecular sequencing data to study evolutionary relationships among groups and organisms' needs to be scaled up to end the AIDS epidemic, according to the participants at a symposium held on 4 June at the New York Academy of Sciences called HIV 2015: Using Phylogenetics to Enhance the HIV Response.


New York Academy of Sciences

HIV 2015: Using Phylogenetics to Enhance the HIV Response, New York, June 4, 2015

New York Academy of Sciences - 2015-06-04

A discussion meeting presented by the Joint United Nations Programme on HIV/AIDS (UNAIDS) and the Microbiology & Infectious Diseases Discussion Group at the New York Academy of Sciences on the use of phylogenetics to enhance HIV response.


KRISP Talks

Seminar: Near Full Length Sequencing to Understand HIV & TB Epidemics In Africa In Real Time

KRISP Talks - 2015-04-30

The Wellcome Trust Africa Centre Genomics & Bioinformatics Programme & UKZN MRC Flagship project cordially invites you to a seminar presented by Prof. Tulio de Oliveira, 30 April 2015, K-RITH building, Nelson R Mandela School of Medicine, Durban, South Africa


UKZN

Ground-breaking PhD Study helps Rural Doctors monitor HIV Drug Resistance

UKZN - 2015-04-17

Dr Justen Manasa graduated with a PhD after completing ground-breaking research in the Hlabisa District of KwaZulu-Natal that resulted in a low cost genotyping method envisaged to help doctors monitor and evaluate drug resistance among HIV-infected patients in resource-limited settings.


SATuRN & CAPRISA

Report on the SATuRN & CAPRISA HIV & TB Advanced Clinical Care Workshop

SATuRN & CAPRISA - 2015-04-13

The Southern Africa Treatment and Resistance Network (SATuRN) and the Centre for the AIDS Programme of Research in South Africa (CAPRISA) organized a HIV & TB Advanced Clinical Care Workshop. This workshop is funded by the Centers for Disease Control and Prevention (CDC) & PEPFAR program in South Africa.


Illumina User Meeting

Our genomics and bioinformatics research program was selected as a keynote presentation in the 1st South African Illumina User Group Meeting, 2015

Illumina User Meeting - 2015-03-31

By: Tulio de Oliveira, Franschoek, South Africa, 31 March 2015 - Continuing advances in next generation genomic analysis are rapidly changing the way we approach our research. The setup of our high-throughput genomics facility at the Nelson R Mandela School of Medicine, in collaboration with Africa Centre and Health and Population Studies allowed our research group to produce HIV-1 complete genomes at an unprecedented scale.


KRISP Talks

Seminar: Whole genome sequence interrogation of drug resistant Mycobacterium tuberculosis

KRISP Talks - 2015-03-20

The Wellcome Trust Africa Centre Genomics & Bioinformatics Programme & UKZN MRC Flagship project cordially invites you to a seminar presented by Prof. Samantha Sampson, 20 February 2015, K-RITH building, Nelson R Mandela School of Medicine, Durban, South Africa


KRISP Talks

Seminar: Virus and host genetics: where and how to look in big data for associations with infectious disease

KRISP Talks - 2015-02-13

The Wellcome Trust Africa Centre Genomics & Bioinformatics Programme & UKZN MRC Flagship project cordially invites you to a seminar presented by Prof. Paul Kellam, 13 February 2015, K-RITH building, Nelson R Mandela School of Medicine, Durban, South Africa


KRISP Talks

Seminar: An Unexpected Influence of Genome Secondary Structure on Recombination in HIV

KRISP Talks - 2015-01-09

The Wellcome Trust Africa Centre Genomics Programme & UKZN MRC Flagship project cordially invites you to a seminar presented by Prof. Darren Martin, 9 January 2015, K-RITH building, Nelson R Mandela School of Medicine, Durban


KRISP Talks

Seminar: Whole genome sequence interrogation of drug resistant Mycobacterium tuberculosis

KRISP Talks - 2014-11-21

The Wellcome Trust Africa Centre Genomics Programme & UKZN MRC Flagship project cordially invites you to a seminar presented by Samantha Sampson, 21 November 2014, Susser & Stein Seminar Room, K-RITH building, Nelson R Mandela School of Medicine, Durban


SATuRN & AWACC

AWACC & SATuRN conference a success! Please see twitter summary

SATuRN & AWACC - 2014-10-13

SATuRN annual workshop run in partnership with AWACC (UKZN, NDoH & Harvard). In total 346 participants attended the two days workshop. The workshop discussions were also very good. Here, we summarize the Tweeter coverage of the event, which contains information on the topics discussed and questions raised.


KRISP Talks

Seminar: Transcriptional profiling in human tuberculosis

KRISP Talks - 2014-10-10

The Wellcome Trust Africa Centre Genomics Programme & UKZN MRC Flagship project cordially invites you to a seminar presented by Prof. Robert J Wilkinson, 10 October 2014, K-RITH building, Nelson R Mandela School of Medicine, Durban


SATuRN & Harvard

Doris Duke Annual Seminar for Medical Students from Harvard and UKZN

SATuRN & Harvard - 2014-10-09

Each year during AWAAC, the Doris Duke International Research Fellowship at Harvard Medical School sponsors a special seminar for medical students who will be attending the conference. During the seminar, invited faculty members discuss journals article that they select with a group of medical students from the US who are engaging in research in sub-Saharan Africa and a group of South African medical students from UKZN. This year 20-25 students will attend the seminar.


KRISP Talks

Seminar: ARV Therapy Initiated Before 2-Months-of-Age Reduces Transcriptionally Active HIV-1 DNA Persistence

KRISP Talks - 2014-09-19

The Wellcome Trust Africa Centre Genomics Programme & UKZN MRC Flagship project cordially invites you to a seminar presented by Prof. Gert Van Zyl, 19 September 2014, K-RITH building, Nelson R Mandela School of Medicine, Durban


KRISP Talks

Seminar: Nanotechnology and the Treatment of HIV Infection

KRISP Talks - 2014-08-22

The Wellcome Trust Africa Centre Genomics Programme & UKZN MRC Flagship project cordially invites you to a seminar presented by Dr. Louis Chonco Jimenez, 22 August 2014, K-RITH building, Nelson R Mandela School of Medicine, Durban


WTAC, UCL, LSHTM & UKZN

Postdoc Fellowship available - HIV Genomics & Bioinformatics I

WTAC, UCL, LSHTM & UKZN - 2014-07-26

We invite applications from ambitious post doctoral scientists, to undertake research in a Flagship programme of the Wellcome Trust & MRC in South Africa.This Fellowship aims to apply and develop bioinformatics software applications to analyze large datasets of complete HIV-1 genomes.


WTAC, UCL, LSHTM & UKZN

Postdoc Fellowship available - HIV Bioinformatics & Phylogenetics II

WTAC, UCL, LSHTM & UKZN - 2014-07-26

We invite applications from ambitious post doctoral scientists, to undertake research in a Flagship programme of the Wellcome Trust & MRC in South Africa.This Fellowship aims to develop and/or apply phylogenetic software applications to create a framework to identify epidemiologically important HIV strains.


WTAC, UKZN, FioCruz, CNPQ

Postdoc Fellowship available - HIV & HTLV Bioinformatics & Phylogenetics III

WTAC, UKZN, FioCruz, CNPQ - 2014-07-26

We invite applications from ambitious post doctoral scientists, to undertake research in a collaborative programme of the the Wellcome Trust Africa Centre and the FioCruz Foundation in South Africa and Brazil.This fellowship aims to apply and develop bioinformatics software applications to analyze large datasets of HIV-1 and HTLV-1 complete genomes


SATuRN

SATuRN Newsletter, Jul 2014: Annual HIVDR Workshop, News, Publications & Blogs

SATuRN - 2014-07-24

The newsletter idea is that anyone with 15 minutes to spare can learn about our work and its application in everyday life. In our second issue of 2014 (Vol. 3 Num. 2), we advertise our annual workshop, which will be presented as part of the Annual Workshop on Advanced Clinical Care - AIDS (AWACC), Durban, 8-9 Oct 2014. We also included interesting news, blogs and publications produced by our network and partners.


NICD

NICD accredited by WHO for HIVDR testing using DBS specimens

NICD - 2014-07-20

By Anna Salimo, South Africa, 20 July 2014. The NICD laboratory in Johannesburg has been performing HIV-1 drug resistance (HIVDR) testing for surveillance purposes using plasma or serum specimens. The World Health Organization (WHO) have adjusted their requirements for accreditation to include HIVDR testing on dried blood spots (DBS) due to their ease of collection, handling, transportation and storage.


WT Africa Centre, UCL & LSHTM

Postdoctoral Research Fellows in HIV

WT Africa Centre, UCL & LSHTM - 2014-07-17

We invite applications from ambitious clinical or non-clinical postdoctoral scientists, to undertake research in a Flagship programme of the Wellcome Trust & MRC in South Africa


KRISP Talks

Seminar: Genome-wide association study indicates two novel resistance loci for severe malaria

KRISP Talks - 2014-07-15

KRISP Talks by Prof. Andreas Ziegler, 1 August 2014, Council Chambers, Westville Campus, UKZN, Durban.


UKZN

Inaugural Lecture: Bioinformatics, Genomics and HIV Research in Africa: A Brief Personal History

UKZN - 2014-07-14

The Vice-Chancellor and Principal Professor Malegapuru Makgoba cordially invites you and your spouse/partner to attend an inaugural lecture presented by Professor Tulio de Oliveira, 30 July 2014, K-RITH, Durban


WTAC & UVRI

Bioinformatics in the Tropics blog: Molecular Evolution & Phylogenetics Workshop Entebbe Uganda 7th-10th April 2014

WTAC & UVRI - 2014-06-25

By: Deogratius Ssemwanga, Jonathan Kayondo, Siva Danaviah and Jaffer Zaidi. The bioinformatics in the tropics series is part of a south-to-south capacity building programme to develop the next generation of bioinformaticians in Africa and Latin America.


KRISP Talks

Seminar: Genomics & Bioinformatics: The need to engage biologists, mathematicians & computer scientists.

KRISP Talks - 2014-06-25

The Wellcome Trust Africa Centre Genomics Programme, the UKZN MRC Flagship project and School of Mathematics, Statistics and Computer Science, UKZN, cordially invites you to a seminar presented by Prof. Tulio de Oliveira, 7 July 2014, UKZN, Pietermaritzburg, South Africa


KRISP Talks

Seminar: Cause-specific mortality: Standardised measurements and comparisons

KRISP Talks - 2014-04-09

The Wellcome Trust Africa Centre Deputy Director iShare Programme cordially invites you to a seminar presented by Prof. Peter Byass, 09 April 2014, Africa Centre headquarters, Mtubatuba


SATuRN

SATuRN Newsletter, Mar 2014: News, publications, videos & new seminar series!

SATuRN - 2014-04-02

The newsletter idea is that anyone with 15 minutes to spare can learn about our work and its application in everyday life. In our first issue of 2014 (Vol. 3 Num. 1) our newsletter we focus on our new seminar series and publications and results from SATuRN partners. We also included interesting news, blogs, reports, tweets and training information produced by our network.


KRISP Talks

Seminar: Old and new challenges for HIV control

KRISP Talks - 2014-04-01

The Wellcome Trust Africa Centre for Health and Population Studies and the University of KwaZulu-Natal (UKZN) cordially invites you to a seminar presented by Prof. Peter Piot, 1 April 2014, Africa Centre headquarters, Mtubatuba


WTAC Genomics Programme

From sample to sequencing: an introduction to Longhorn's primesuite of technologies

WTAC Genomics Programme - 2014-03-28

The Wellcome Trust Africa Centre Genomics Programme & UKZN MRC Flagship project cordially invites you to a presentation, 28 March 2014, Durban


KRISP Talks

Seminar: Next-generation sequencing for identifying drug resistance in Mycobacterium Tuberculosis

KRISP Talks - 2014-03-28

The Wellcome Trust Africa Centre Genomics Programme & UKZN MRC Flagship project cordially invites you to a seminar, 28 March 2014, Durban


KRISP Talks

Seminar: Unlocking the potential of TB genomics

KRISP Talks - 2014-03-27

The Wellcome Trust Africa Centre Genomics Programme & UKZN MRC Flagship project cordially invites you to a seminar presented by Dr. Siva Danaviah, 26 March 2014, Africa Centre headquarters, Mtubatuba


KRISP Talks

Seminar: Trends and causes of hospitalisation in adults receiving ART

KRISP Talks - 2014-03-19

The Wellcome Trust Africa Centre Population Epidemiology Programme & UKZN MRC Flagship project cordially invites you to a seminar presented by Dr. Portia Mutevedzi, 19 March 2014, Africa Centre headquarters, Mtubatuba


K-RITH

Interactive Biostatistics Course, Durban, 26-30 may 2014

K-RITH - 2014-03-13

K-RITH is offering an innovative course in the biostatistical methods used in medical research. This hands-on course is taught by Harvard biostatistician, Dr. Lori Chibnik.


KRISP Talks

Seminar: Multi-step inhibition explains HIV-1 protease inhibitor pharmacodynamics and resistance

KRISP Talks - 2014-03-12

The Wellcome Trust Africa Centre Genomics Programme & UKZN MRC Flagship project cordially invites you to a seminar presented by Dr. Justen Manasa, 12 March 2014, Africa Centre headquarters, Mtubatuba


KRISP Talks

Seminar: HIV-1 Transmission during Early Infection in Men Who Have Sex with Men: A Phylodynamic Analysis

KRISP Talks - 2014-02-19

The Wellcome Trust Africa Centre Genomics Programme & UKZN MRC Flagship project cordially invites you to a seminar presented by Dr. Eduan Wilkinson, 19 February 2014, Africa Centre headquarters, Mtubatuba


KRISP Talks

Seminar: 30 years of HIV diversity research: a personal perspective

KRISP Talks - 2014-01-31

The Wellcome Trust Africa Centre Genomics Programme & UKZN MRC Flagship project cordially invites you to a seminar presented by Prof. Susan Engelbrecht, 31 January 2014, Durban


CAIR/UKZN & Africa Centre

PhD and/or MSc Scholarship available - Computer Science

CAIR/UKZN & Africa Centre - 2014-01-16

The causes and consequences of HIV transmission and drug resistance - Computer Science PhD and/or MSc studentships available at UKZN/CSIR Meraka Centre for Artificial Intelligence Research (CAIR) in collaboration with Wellcome Trust Africa Centre for Health and Population Studies. Funded by a MRC Flagship research project. Potential Supervisors: Dr. Deshen Moodley & Prof. Hugh Murrell, CAIR, UKZN


KRISP Talks

Seminar: Implementing HIV-1 Genotypic Resistance Testing in Antiretroviral Therapy Programs in Africa: Needs, Opportunities, and Challenges.

KRISP Talks - 2014-01-15

The Wellcome Trust Africa Centre Genomics Programme & UKZN MRC Flagship project cordially invites you to a seminar presented by Prof. Tulio de Oliveira, 15 January 2014, Africa Centre headquarters, Mtubatuba


UVRI

Bioinformatics in the Tropics Uganda 2014, UVRI, Entebbe, Uganda, 7th to 10th April 2014

UVRI - 2014-01-06

This is a series of four workshops, which will be presented in Brazil (2013 & 2014), South Africa (2013) and Uganda (2014) as part of a south to south capacity building programme to develop the next generation of bioinformaticians in Africa and Latin America. The objective is to train post-doctoral researchers to become trainers and post-graduate students to use bioinformatics and phylogenetic software applications needed for their research.


SATuRN

SATuRN Newsletter, Dec 2013: News, workshops, manuscripts & PhD/MSC positions available!

SATuRN - 2014-01-06

The newsletter idea is that anyone with 15 minutes to spare can learn about our work and its application in everyday life. In our last issue of 2013 our newsletter we focus on our capacity building programme. We also advertise 7 PhDs and 4 MScs positions in this issue!


UKZN & Africa Centre

PhD Scholarship available - Genomics, Bioinformatics & Epidemiology II - HIV dynamics

UKZN & Africa Centre - 2013-12-13

The causes and consequences of HIV transmission and drug resistance - PhD studentship available for Genomics, Epidemiology and Bioinformatics at UKZN for the MRC Flagship research project. Supervisors: Prof. Tulio de Oliveira & Prof. Frank Tanser, Africa Centre, UKZN


UKZN & Africa Centre

PhD Scholarship available - Genomics, Bioinformatics & Epidemiology I - HIV Drug Resistance

UKZN & Africa Centre - 2013-12-13

The causes and consequences of HIV transmission and drug resistance - HIV Drug resistance PhD studentship at Wellcome Trust Africa Centre for Health and Population Studies, University of KwaZulu-Natal (UKZN). Funded by a MRC Flagship research project. Supervisors: Prof. Tulio de Oliveira & Prof. Frank Tanser, Africa Centre, UKZN


UKZN Genetics & Africa Centre

PhD and/or MSc Scholarship available - Human Genetics

UKZN Genetics & Africa Centre - 2013-12-13

The causes and consequences of HIV transmission and drug resistance - Human Genetics PhD and/or MSc studentships available at UKZN Genetics department in collaboration with Wellcome Trust Africa Centre for Health and Population Studies. Funded by a MRC Flagship research project. Supervisors: Dr. Paula Sommer, Genetics Department, UKZN & Prof. Tulio de Oliveira, Africa Centre, UKZN


HEARD & Africa Centre

PhD and/or MSc Scholarship available - Social Sciences

HEARD & Africa Centre - 2013-12-13

The causes and consequences of HIV transmission and drug resistance - Social Sciences PhD and/or MSc studentships available at HEARD/UKZN Genetics department in collaboration with Wellcome Trust Africa Centre for Health and Population Studies. Funded by a MRC Flagship research project. Potenital Supervisors: Dr Kaymarlin Govender, Ms Samantha Willan & Mr. Andrew Gibbs, HEARD, UKZN.


Mail & Guardian

SA Medical Research Council Scientific Awards

Mail & Guardian - 2013-12-08

In his address to MRC award and grant winners at a prestigious ceremony in Cape Town, outgoing MRC Chairperson Professor Lizo Mazwai described the South African Medical Research Council (MRC) as 'richer, more focused, more efficient and better placed to deliver a healthy nation through research.'


Sunday Times

Heroes in the battle for health

Sunday Times - 2013-12-01

There have been major successes in the fight agains the disease since it was first identified in 1983. Bianca Capazorio speaks to some young South Africans at the forefront of work in the field.


UKZN

Putting the I into HIV - World Aids Day UKZN

UKZN - 2013-11-30

Leading scientists in HIV/AIDS research discussed the diversity of the HIV epidemic, new scientific evidence and the promising interventions on the horizon to tackle it.


K-RITH

'An HIV-1 vaccine is possible' says Prof Thumbi Ndung'u at UKZN AIDS Day 2013

K-RITH - 2013-11-29

Ahead of World AIDS Day 2013, leading HIV/AIDS researchers in Durban have urged society to focus on insights, innovation and integrity in the journey into an HIV-free future and to put people at the centre of health services.


AIGHD

SATURN-PASER unites international minds & reveals potential resistance free HIV drug

AIGHD - 2013-11-26

By Inez Rossouw, 26 Nov 2013, Bloemfontein - Dolutegravir, a drug aimed against the human immunodeficiency virus (HIV), might not elicit any resistance to it. This was revealed at the Southern African HIV/TB drug resistance and monitoring workshop hosted by the Southern African Treatment and Resistance Network (SATuRN) at the Medical School of the University of the Free State.


UFS news

DNA sequencer launched at the University of Free State

UFS news - 2013-11-25

The University of the Free State (UFS) can now collect immensely valuable data on drug resistance in HIV/Aids and TB with the new DNA sequencer that was launched recently at the International workshop on HIV/AIDS and TB drug resistance at the Bloemfontein Campus.


UFS Press Release

International Workshop in Bloemfontein to Translate Research and Clinical Knowledge into Clinical Practice to Fight HIV & TB Drug Resistance in Africa

UFS Press Release - 2013-11-19

BLOEMFONTEIN, 21 November 2013. Today, a large intentional workshop on HIV & TB drug resistance starts, which will bring some of the top international researchers, clinicians and policy makers to the University of the Free State in order to discuss strategies to manage and prevent drug resistance in Africa.


UKZN, CAPRISA & HEARD

A UKZN panel discussion: Bringing the 'I' into HIV - New approaches in developing person-centred interventions to fight the HIV epidemic

UKZN, CAPRISA & HEARD - 2013-11-08

A UKZN panel discussion on 26 November 2013: 'Bringing the 'I' into HIV - New approaches in developing person-centred interventions to fight the HIV epidemic' as part of World AIDS Day 2013 activities.


SAFM

SAFM Radio Interview with Prof. Tulio de Oliveira on their HIV Drug Resistance and Transmission Research and Award

SAFM - 2013-11-03

Radio interview by Sisanda Jonas at SAfm weekend pmlive show 3 Nov 2013


MRC

The SA Medical Research Council announces funding of R190 million for high impact research projects

MRC - 2013-11-01

The MRC has established a new high-profile R190 million funding opportunity for Medical Schools and Universities to undertake 'Flagship Projects' aimed at addressing South Africa's key health problems. The winning projects, led by some of South Africa's most accomplished scientists, were announced at a media briefing at the MRC in Cape Town on Wednesday evening.


Africa Centre & UKZN DVC

16.5 million rand to convert cutting-edge HIV research in rural South Africa into national policy

Africa Centre & UKZN DVC - 2013-10-31

Professor Salim Abdool Karim and Health Minister, Dr Aaron Motsoaledi, awarded a R16.5 million grant to fight HIV drug resistance and transmission in rural KwaZulu-Natal.


UKZN

Multi-million rand award to UKZN scientists for Cutting-Edge HIV Research

UKZN - 2013-10-30

Professor Frank Tanser and Professor Tulio de Oliveira from UKZN's Africa Centre for health and Population studies were recently awarded a large grant to fight HIV drug resistance and transmission in rural KwaZulu-Natal. The grant, funded by the Medical Research Council (MRC) Flagship Projects is part of the MRC's strategy to sustain vibrant medical research in South Africa.


K-RITH

BioMedical research is undergoing a revolution

K-RITH - 2013-10-25

'Intensive', 'Comprehensive', 'Fulfilling' and 'Exciting' were just some of the words used by students to describe the first Bioinformatics course hosted by the KwaZulu-Natal Research Institute for TB and HIV (K-RITH) in partnership with the US-based Broad Institute and the NIH recently.


SATuRN

Newsletter, Oct 2013: News, blogs, manuscripts & Youtube videos!

SATuRN - 2013-10-01

The concept behind this newsletter is that anyone with 15 minutes to spare can learn about the work of SATuRN. In this third issue of 2013 our newsletter we focus on our digital videos activities. We have also included interesting news, blogs, reports, tweets, publications and training information produced by our network.


Wellcome Trust

New Director named for leading HIV research centre in South Africa

Wellcome Trust - 2013-09-02

Deenan Pillay, Professor of Virology at UCL (University College London), is today named as the new Director of the Africa Centre for Health and Population Studies, one of the Wellcome Trust's major overseas programmes.


SATuRN

SATuRN Newsletter, Aug 2013: Special Edition - Training and Capacity Building

SATuRN - 2013-08-06

The concept behind this newsletter is that anyone with 15 minutes to spare can learn about the work of SATuRN. The newsletter is presented as a PDF document with links to complete articles at the bioafrica.net website.


Southern African Journal of HIV Medicine

BOOK REVIEW - HIV & TB Drug Resistance & Clinical Management Case Book

Southern African Journal of HIV Medicine - 2013-06-20

by Sigaloff & Hamers, The Southern African Journal of HIV Medicine, Book Review on the HIV & TB Drug Resistance & Clinical Management Case Book by Rossouw, Lessells and de Oliveira


Africa Centre/SATuRN

Bioinformatics in the tropics II: Large data sets analysis workshop: HIV phylogenetics and drug resistance, Durban, South Africa, 23-26 Sept 2013

Africa Centre/SATuRN - 2013-06-02

This is the second workshop of the bioinformatics in the tropics series, which will be presented by the Wellcome Trust Africa Centre for Health and Population Studies at K-RITH at the University of KwaZulu-Natal, Durban, South Africa, 23 to 27 September 2013. The bioinformatics in the tropics series is part of a south to south capacity building programme to develop the next generation of bioinformaticians in Africa and Latin America.


FioCruz

Bioinformatics in the tropics I: 1st International Bioinformatics & Molecular Viral Evolution Workshop, Salvador, Bahia, Brazil, 22-26 July 2013

FioCruz - 2013-06-01

This is the first workshop of the bioinformatics in the tropics series, which will be presented at the Oswaldo Moniz Research Center (CPqGM), Oswaldo Cruz Foundation (FIOCRUZ), Salvador, Bahia, Brazil, 22 to 26 July 2013.


Bioinformatics in the Tropics

Bioinformatics in the tropics workshop series 2013-2014

Bioinformatics in the Tropics - 2013-05-30

This is a series of four workshops, which will be presented in Brazil (2013 & 2014), South Africa (2013) and Uganda (2014) as part of a south to south capacity building programme to develop the next generation of bioinformaticians in Africa and Latin America.


Wellcome Trust

Infectious Disease Genomics and Global Health Wellcome Trust Conference

Wellcome Trust - 2013-05-24

We are pleased to announce that we are presenting at the Sixth Infectious Disease Genomics and Global Health conference, Cambridge, U.K, 16-18 October 2013. The focus of this meeting is the application of genomic technologies to the problems of infectious disease in a global health context.


International Innovation

The Network Marker

International Innovation - 2013-04-22

Drug resistance poses significant potential problems in the fight against HIV and TB, but little is known about how best to tackle it. Dr Tulio de Oliveira heads a network that aims to fill this knowledge gap.


Zululand Observer

Case book tackles HIV and TB drug resistance

Zululand Observer - 2013-04-15

By Jonathan Davis, 15 April 2013 - Researchers from the Africa Centre for Health and Population Research near Mtubatuba have published a important book to help rural doctors, nurses and pharmacists working on the frontline of the country's interlinked HIV and tuberculosis (TB) pandemics manage increasing levels of resistance to the drugs needed to fight the diseases.


SATuRN

SATuRN Newsletter, Mar 2013: News, blogs, events, publications and a case book on HIV/TB drug resistance

SATuRN - 2013-04-01

The concept behind this newsletter is that anyone with 15 minutes to spare can learn about the work of SATuRN. The newsletter is presented as a PDF document with links to complete articles at the bioafrica.net website.


RUDASA

SATuRN will have a session at the 17th Rural Health Conference

RUDASA - 2013-03-31

The 17th Annual Rural Health Conference will be held in St. Lucia, KwaZulu-Natal, South Africa, from 8 to 10 August 2013. SATuRN will have a session (approximately 2-3 hours) in the conference and will distribute the HIV & TB Drug Resistance and Clinical Management Case Book.


University of Pretoria

University of Pretoria and partners launch a book

University of Pretoria - 2013-03-19

By Sanku Tsunke, Pretoria, 19 March 2013. Drug resistance is one of the main challenges confronting HIV and TB programmes in Africa. Facing these challenges requires an understanding of how drug resistance develops, as well as up-to-date knowledge of how to diagnose and manage drug resistance in HIV and TB patients.


PretoriaNews

Casebook aims to curb drug resistance

PretoriaNews - 2013-03-19

Pretoria News - 19 March 2013, DOCTORS from the University of Pretoria (UP) and University of KwaZulu-Natal (UKZN) have stepped up to the challenge of providing a clinical management casebook for health care workers treating patients with HIV and TB drug resistance.


UKZNonline

BOOK ON MANAGEMENT OF HIV AND TB DRUG RESISTANCE LAUNCHED

UKZNonline - 2013-03-16

HIV and TB: Drug Resistance and Clinical Management Case Book - a book co-authored by two academics from the Africa Centre for Health and Population Studies - has been presented to frontline health workers at a workshop in northern KwaZulu-Natal.


UKZN

Transferring Critical Knowledge and Skills to Frontline Medical Personnel Fighting the HIV & TB epidemics in rural South Africa

UKZN - 2013-03-15

UKZN's Africa Centre for Health and Population Studies, based in the College of health Sciences, has once again made huge strides in HIV management. Recently, the Centre's, Dr Richard Lessells and Dr Tulio de Oliveira together with the University of Pretoria's, Dr. Theresa Rossouw; launched a book entitled, 'HIV and TB: Drug Resistance and Clinical Management Case Book'.


Universiteit van Pretoria

Universiteit van Pretoria en vennote stel boek vry oor weerstand teen middels wat gebruik word om MIV en tuberkulose te bekamp

Universiteit van Pretoria - 2013-03-15

Weerstand teen medikasie is een van die belangrikste struikelblokke wat programme om MIV en tuberkulose in Afrika te bestry te bowe moet kom. Om hierdie uitdagings die hoof te bied, word 'n begrip vereis van hoe weerstand teen die middels tot stand kom, sowel as vertroudheid met die jongste metodes om weerstand teen die medikasie in MIV- en tuberkulosepasiente te diagnoseer en bestuur.


Africa Centre

PRESS RELEASE: Book Launch: HIV and TB Drug Resistance & Clinical Management Case Book

Africa Centre - 2013-03-06

Prof Eric Buch, Dean of the Faculty of Health Sciences at the University of Pretoria, in partnership with European Delegation to South Africa, MRC Inflammation and Immunity Unit and the Africa Centre for Health and Population Studies, UKZN, invite members of the media to attend the launch of the 'HIV and TB Resistance & Clinical Management Case Book' that is authored by Dr Theresa Rossouw of UP and Drs Richard Lessells and Tulio de Oliveira of the Africa Centre for Health and Population Studies. The details are as follows:


University of Pretoria

Invitation to the launch of the HIV and TB drug resistance & clinical management case book

University of Pretoria - 2013-03-05

University of Pretoria invites you to attend the launch of the publication HIV and TB resistance & clinical management case book. The invitation is writen in three official South African languages: Afrikaans, English and Sepedi.


Leuven & Univ. Florida

18th International Bioinformatics Workshop on Virus Evolution & Molecular Epidemiology, USA, 25-30 Aug 2013

Leuven & Univ. Florida - 2013-02-27

We are announcing the organization of the international workshop on Virus Evolution and Molecular Epidemiology (VEME) in 2013, hosted by the Emerging Pathogens Institute in the warm city of Gainsville and sponsored by several local partners.


Science

Africa Centre major scientific achievements! Two Science papers showing that antiretroviral therapy increases life expectance and reduces transmission

Science - 2013-02-22

Africa Centre, South Africa, 22 February 2013 - Today, colleagues from the Wellcome Trust Africa Centre for Health and Population Studies have published two breakthrough scientific manuscripts at Science.


SATuRN

HIV/TB Drug Resistance and Clinical Management Workshop & Book Launch, Ghost Mountain Inn, Mkuze, South Africa, 7-8 Mar 2013

SATuRN - 2013-02-18

Organised by the Africa Centre for Health and Population Studies and Southern African Treatment and Resistance Network (SATuRN) in collaboration with the uMkhanyakude District Health Office. This workshop is aimed at developing knowledge and skills around the prevention and management of drug resistance and treatment failure in both HIV and TB.


Pirate Science

Searching for Virus Phylotypes

Pirate Science - 2013-01-22

Viral phylogenies have wide use: studying evolution, tracing the origin of epidemics, establishing dominant mode of transmission, identifying the apparition of drug resistance, even tracking individual body compartments.


ACILT

Practical Course on Quality Assurance of HIV-1 Drug Resistance Interpretation in Sequence Editing and Data Management Processes

ACILT - 2013-01-16

The African Centre for Integrated Laboratory Training (ACILT) present the HIV-1 drug resistance practical course, 22-26 April, Johannesburg, South Africa.


Share

The 2012 Southern African ARV drug resistance testing guidelines

Share - 2013-01-13

Antiretroviral therapy (ART) has converted HIV infection from an almost universally fatal illness to a chronic manageable disease. Adherence to therapy is essential for full viral suppression and optimal immune reconstitution.


MIT Technology review

The Machine That Will Help End TB

MIT Technology review - 2012-12-11

By Jon Cohen on December 11, 2012 - Nearly 1.5 million people die from tuberculosis every year, even though most cases can be cured with routine antibiotic treatments. One country's fight to get the ancient scourge under control has an unlikely hero: a simple diagnostic test.


The Communication Initiative Network

Comminit News: Scientific Community Engagement Activities in Rural KwaZulu-Natal, South Africa

The Communication Initiative Network - 2012-11-30

BioAfrica, Southern African Treatment and Resistance Network (SATuRN), and the Africa Centre Bioinformatics Unit use art to present scientific facts in Rural KwaZulu-Natal, South Africa. They are involved in many community engagement activities, presenting to African communities about the origin of HIV, the causes and consequences of drug resistance development, and how to successfully manage HIV and tuberculosis (TB) treatment.


UKZN

UKZN Research Centres Collaborate to Celebrate World AIDS Day

UKZN - 2012-11-29

The Health Economics and HIV and AIDS Research Division (HEARD) in collaboration with CAPRISA, SATuRN/Africa Centre and the University of KwaZulu-Natal Press hosted Getting to Zero: Showcasing KZN Research on HIV and AIDS on 14 November at the KZNSA Gallery.


TB Union

SATuRN at the 43rd Union World Conference on Lung Health

TB Union - 2012-11-20

KUALA LUMPUR, MALAYSIA, 14-17 Nov 2012, SATuRN researchers Dr. Richard Lessells and Dr. Tulio de Oliveira had a very successful TB conference. In this post we cover their presentations, workshops participation and tweeter coverage.


SATuRN

HIV and TB bioinformatics presentation and tweet coverage at K-RITH opening, 9-11 October 2012

SATuRN - 2012-10-04

SATuRN is presenting a talk at the KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH) opening. This symposium has a fantastic scientific program, with some of the leading researchers and funders in the world! Please follow our tweeter coverage!


LSHTM tbcentre

SATuRN activities at the London School of Hygiene and Tropical Medicine TB Centre

LSHTM tbcentre - 2012-10-01

SATuRN activities were highlighted at the LSHTM TB Centre Annual Retreat, which was held in Downing College, Cambridge.


International Innovation

Dissecting diagnostics - TB drug resistance in rural South Africa

International Innovation - 2012-09-20

Researchers based in northern KwaZulu-Natal in rural South Africa are exploring the impact of novel molecular tuberculosis diagnostic system on clinical outcomes for patients with multidrug-resistance TB.


SATuRN

SATuRN Newsletter, Sept 2012, News, blogs, conferences, publications on HIV/TB drug resistance and phylogenetics

SATuRN - 2012-09-14

In this third issue of our newsletter we have included interesting news, blogs, reports, tweets, publications and training information produced by our network. We hope you enjoy it and find it informative. We welcome any feedback about content or format.


Cape Argus

'Tainted milk' from wet nurse HIV risk

Cape Argus - 2012-08-26

By BIANCA CAPAZORIO - A BABY girl who contracted HIV after being breast-fed by a well-meaning aunt has become the first proven case in SA to have contracted HIV from a surrogate feeder or 'wet nurse'.


SA DoH research brief

Tainted Milk from Surrogate Feeder

SA DoH research brief - 2012-08-25

A baby girl who contracted HIV after being breast-fed by a well-meaning aunt has become the first proven case in South Africa to have contracted HIV from a surrogate feeder or 'wet nurse'. The case contained in new research highlights the importance of HIV testing of mothers and surrogate feeders at a time when the government is phasing out free infant formula in its clinics.


Zululand Observer

Local centre proves 'surrogate' HIV infection

Zululand Observer - 2012-08-24

The Africa Centre for Health and Population Studies, Zululand's HIV-AIDS research hub based near Mtubatuba, has revealed the first proven HIV surrogate transmission case in South Africa.


Wellcome Trust

DNA sequencing confirms HIV transmission through surrogate breastfeeding

Wellcome Trust - 2012-08-23

DNA sequencing has provided evidence of HIV-1 transmission from an infected woman breastfeeding her niece in South Africa, drawing attention to infant feeding practices and the need for HIV testing of all breastfeeding surrogates as well as mothers.


SABC

Breastfeeding in the spotlight

SABC - 2012-08-16

A case where an aunt infected her niece with HIV through breastfeeding has drawn attention to feeding practices in South Africa. The case was published in the medical journal Lancet and highlighted the risk of HIV transmission from a surrogate carer, the Africa Centre for Health and Population Studies said today.


LabMedica

Collaboration to Undertake HIV Resistance Testing in Africa

LabMedica - 2012-08-06

Sequencing-based diagnostics for human immunodeficiency virus (HIV)-infected individuals will be carried out in Africa in order to determine resistance to antiretroviral drugs.


CAPRISA

Creating access to HIV/TB drug resistance testing

CAPRISA - 2012-08-01

During July, the acclaimed researcher, Dr Tulio de Oliveira from the Southern African Treatment Research Network (SATuRN), was invited to CAPRISA to visit CAPRISA's eThekwini Clinical Research Site. He also presented latest developments on affordable HIV and TB drug resistance testing and open access, public, drug resistance databases to CAPRISA's management team, followed by discussions on possible opportunities for collaboration.


Doctor's Guide Global Edition

Drug Resistance After Failure of First-Line ART Increasing in Rural South Africa: Presented at AIDS 2012

Doctor's Guide Global Edition - 2012-07-27

By Nancy A. Melville - WASHINGTON, DC - July 27, 2012 - As antiretroviral therapy (ART) for HIV becomes widely accessible in Southern Africa, the risk for drug resistances is on the rise, and as many as 1 in 6 adults show acquired drug resistance to standard second-line drug regimens, researchers said here on July 24 at the 19th International AIDS Conference.


GenomeWeb

Life Tech, SATuRN Collaborate on Dx for Antiretroviral Resistance in HIV in Africa

GenomeWeb - 2012-07-26

NEW YORK (GenomeWeb News) - Life Technologies today announced a collaboration with the Southern African Treatment and Resistance Network (SATuRN) covering sequencing-based diagnostics for HIV patients in Africa.


Reuters

Life Technologies Corporation And Southern African Treatment and Resistance Network Collaborate To Increase Access To HIV Testing In Africa

Reuters - 2012-07-24

Life Technologies Corporation announced a collaboration with the Southern African Treatment and Resistance Network (SATuRN) on sequencing-based diagnostics for HIV-infected individuals in Africa.


The Wall Street Journal

Life Technologies and SATuRN Collaborate to Increase Access to HIV Testing in Africa

The Wall Street Journal - 2012-07-24

Life and Southern African Treatment and Resistance Network (SATuRN) Partner in Sequencing-Based Surveillance of Drug Resistance


Los Angeles Times

HIV drug resistance is spreading in Africa, experts say

Los Angeles Times - 2012-07-23

WASHINGTON (By Erin Loury, LA Times) - Scaling up the distribution of HIV medication over the last decade has vastly increased the number of people receiving treatment around the world. An estimated 8 million infected people received the antiretroviral drugs in 2011, compared to just 400,000 in 2003.


BBC

Drug-resistant HIV 'on increase' in sub-Saharan Africa

BBC - 2012-07-22

Drug-resistant HIV has been increasing in parts of sub-Saharan Africa over the last decade, according to experts writing in the Lancet


SATuRN

SATuRN meeting, presentations & tweet coverage at the XIX International AIDS 2012 Conference, Washington

SATuRN - 2012-07-14

WASHINGTON, 22-27 July 2012 - We are hosting a meeting, presenting many talks and posters and tweeting on the XIX International AIDS 2012 Conference.


SATuRN

SATuRN Newsletter V.1 Num.2 (Apr-Jun 2012) - Featured partners, news, blogs, tweets & publications

SATuRN - 2012-07-02

In this second issue of our newsletter we have included interesting news, blogs, reports, tweets, publications and training information produced by our network. We hope you enjoy it and find it informative. We welcome any feedback about content or format.


Africa Health Placements

SAHIVSOC'S First Conference, 25-28 November 2012, Cape Town ICC

Africa Health Placements - 2012-07-02

The Southern African HIV Clinicians Society will be hosting its first Conference: Striving for Clinical Excellence, 25-28 November 2012 at the Cape Town ICC.


SATuRN

SATuRN's tweet coverage about drug resistance at the 3rd SA TB conference

SATuRN - 2012-06-15

We participated, presented and tweeted about the 3rd South African TB conference, 12-15 June 2012, ICC, Durban. We had covered all the sessions that present TB drug resistance results. Please find below our tweets from our participation in our national TB conference.


BioAfrica

BioAfrica Art & Science section is open!

BioAfrica - 2012-05-10

In this exciting new section of bioafrica.net art we feature creative projects that celebrate, investigate and/or communicate biomedical science. Here, we share blogs, news articles, tweets, audio and audiovisual media to increase public awareness of innovative collaborations between art and science.


BioAfrica

SATuRN Newsletter Vol. 1 Number 1, Jan-Mar 2012

BioAfrica - 2012-04-15

The newsletter idea is that anyone with 15 minutes to spare can learn about our work and its application in everyday life.


MSF

Open letter on urgent need for compassionate use of bedaquiline for XDR-TB and pre-XDR-TB in South Africa

MSF - 2012-04-11

BioAfrica & SATuRN Supports this Open Letter!

Open letter to the Medicines Control Council and Ministry of Health on urgent need for compassionate use of bedaquiline for XDR-TB and pre-XDRTB in South Africa.


IAS

Transmitted Drug Resistance Rate Remains Below 5% in South Africa

IAS - 2012-03-05

by Mark Mascolini - Analysis of South Africans with newly diagnosed, untreated HIV infection indicates low levels of transmitted antiretroviral-resistant HIV across the country through 2010 and no evidence of transmitted drug-resistant HIV in rural KwaZulu Natal


UKZN

Highly Specialized Team to Tackle HIV Drug Resistance Problem in Southern Africa

UKZN - 2012-02-22

DURBAN, SOUTH AFRICA, 24-26 FEB 2012 - A small, highly specialized multidisciplinary team of doctors and statisticians from South Africa, Botswana, the USA and the UK will meet in Durban this weekend with the express purpose of pooling their resources, knowledge and expertise in an attempt to improve understanding the problem of HIV drug resistance in southern Africa.


BioAfrica

New and interactive section of BioAfrica and SATuRN website

BioAfrica - 2012-01-14

One of our main aims for this development is for users and collaborators to become more involved in the website. It has added over 100 new webpages to bioafrica.net, including blogs, open access publications, media coverage, clinical cases tutorials and twitter. It has also increased the number of people collaborating in the development of our website!


News24 City Press

Alarm bells on HIV-drug resistance - Study raises fears as patients develop immunity to antiretroviral therapy

News24 City Press - 2011-11-06

JOHANNESBURG - The prevalance of HIV-positive people who have developed a resistance to life-prolonging antiretroviral treatment (ART) is a cause for concern for South Africa, scientists warn.


CDC - South Africa

Meeting to Discuss the Growing Threat of HIV & TB Drug Resistance in South Africa and Botswana

CDC - South Africa - 2011-11-04

JOHANNESBURG - A group of renowned HIV and TB scientists, public health officials and physicians will meet at the University of Botswana in Gaborone, this coming Monday and Tuesday (7th & 8th of November) to discuss the growing problem of HIV and TB drug resistance in southern Africa.


Mmegionline

Botswana hosts Africa HIV/TB drug resistance workshop

Mmegionline - 2011-11-04

GABARONE - For the first time, Botswana is hosting the Africa HIV/TB Drug Resistance and Clinical Management workshop. The two-day workshop started yesterday at the University of Botswana (UB). Scientists, public health officials and physicians from across the world are attending the event to discuss the growing problem of HIV and TB drug resistance in Southern Africa.


AIDSmap

Drug Resistance Increasing in Children

AIDSmap - 2011-06-27

Indeed, drug resistance is emerging in children on ART in South Africa.


Zululand Observer

Taxis on board - Spreading the word while jiving

Zululand Observer - 2011-03-20

Jiving with Science is a new public engagement initiative of the Africa Centre for Health and Population Studies. Africa Centre is an international HIV research facility with a partnership HIV testing, treatment and care programme run jointly with the KZN Department of Health. The Mtubatuba-based centre is where the HIV epidemic is one of the most severe in the world, with nearly one in two adults aged 35-40 being infected.


SA DoH research brief newsletter

Jiving with Science is a new public engagement initiative of the Africa Centre for Health and Population Studies

SA DoH research brief newsletter - 2011-03-08

Jiving with Science is a new public engagement initiative of the Africa Centre for Health and Population Studies. The Africa Centre, a joint project of the University of KwaZulu-Natal (UKZN) and the Medical Research Council of Southern Africa, is an international HIV research facility with a partnership HIV testing, treatment and care programme run jointly with the KwaZulu-Natal Department of Health.


UKZN

JIVING WITH SCIENCE - Music CDs

UKZN - 2011-03-04

Jiving with Science is a new public engagement initiative of the Africa Centre for Health and Population Studies. The Africa Centre, a joint project of the UKZN and the Medical Research Council of Southern Africa, is an international HIV research facility with a partnership HIV testing, treatment and care programme run jointly with the KZN Department of Health. It is based in rural, northern KwaZulu-Natal where the HIV epidemic is one of the most severe in the world with nearly one in two adults aged 35-40 being infected.


Zululand Observer

Stirring students with science

Zululand Observer - 2010-06-18

RICHARDS BAY - A team from Africa Centre for Health and Population Studies explained the origins of Human Immunodeficiency Virus (HIV) for scholars of the Aiglon Society at Grantleigh College last Tuesday. The challenge to incorporate high-level bioinformatics and molecular evolutionary analysis into a high-school format of genetic variation and HIV life cycle was facilitated by senior researcher, Dr Tulio de Oliveira.


Center for Global Development

The Race Against Drug Resistance

Center for Global Development - 2010-06-14

by Rachel Nugent, Emma Back, and Alexandra Beith - In an increasingly interconnected world, drug resistance does not stop at a patient's bedside, it threatens global health. It has slowed gains against the fatal ravages of childhood dysentery and pneumonia, drastically increased the costs of fighting tuberculosis and malaria, and imperiled efforts to effectively treat people living with HIV/AIDS. Tens of millions of lives are at stake; quality of life for scores of millions more is under threat.


Die Burger

Believe in ART, get tested please

Die Burger - 2008-09-10

CAPE TOWN - Believe that anti-retroviral treatment (ART) medication works and get yourself tested. People who are infected with the virus are able to live longer, healthier lives, provided they use their medication and seek treatment early enough. This was the key message Dr. Tulio de Oliveira, a bio-informatics researcher from SATuRN wanted to be convey to the general public.


Nature

High noon in Libya

Nature - 2007-07-19

This week sees yet another crisis point in the Libyan case of six foreign health professionals sentenced to death on charges of injecting hundreds of children with HIV. Declan Butler traces the efforts of scientists to help establish the truth.


Cape Times

World-class scientist due to join UWC team tackling HIV/Aids treatment in SA.

Cape Times - 2007-01-14

CAPE TOWN - A world-class molecular biologist whose research on HIV and anti-retrovirals (ARVs) could dramatically improve the treatment of HIV/Aids in South Africa. Doctor Tulio de Oliveira, an expert in bioinformatics at Oxford University, will join the SA National Bioinformatics Institute at UWC.


Science

Genetic Analysis Clears Accused Medics

Science - 2006-12-20

A new molecular study provides the strongest scientific evidence yet that six foreign medics held in Libya are innocent of charges that they deliberately infected more than 400 children with HIV. Accumulated mutations in the virus genomes reveal that the outbreak began well before the medics arrived in the country. The Libyan supreme court is set to decide on 19 December whether to execute the medics. It is unclear whether the new study will influence its verdict.


New Scientist

New evidence in Libyan HIV trial

New Scientist - 2006-12-20

New and compelling scientific evidence has emerged in support of five Bulgarian nurses and a Palestinian doctor accused of deliberately spreading HIV to 426 Libyan children in 1998.


BBC

Libya sentences medics to death

BBC - 2006-12-19

A Libyan court has sentenced five Bulgarian nurses and a Palestinian doctor to death for knowingly infecting hundreds of Libyan children with HIV.


The Guardian

Medics face death while Libya uses HIV children as diplomatic pawns

The Guardian - 2006-12-17

Alex Duval Smith The Observer, Sunday 17 December 2006 13.12 GMT - The death in Libya six weeks ago of nine-year-old Marwa Annouiji from Aids was much more than just another developing world statistic. In her short, life, dominated by illness, the frail child was a pawn in a high-level game of international relations. Marwa, from al-Bayda on the Mediterranean coast, was the 52nd Libyan child to die as a result, Libya claims, of a deliberate operation by foreign medical workers to pump HIV-infected blood into 426 girls and boys at the al-Fatah Hospital in Benghazi.


University of Oxford - BluePrint News

New scientific evidence in Libya HIV death penalty case

University of Oxford - BluePrint News - 2006-12-07

OXFORD - New molecular evidence from Oxford Zoology Department casts significant doubt on charges against six medical workers who are facing execution in Libya. The medical workers are charged with deliberately contaminating more than 400 children with HIV in 1998.However, new evidence published online in Nature from the Evolutionary Biology Group at Oxford, in collaboration with several European universities, shows that the subtype of HIV involved began infecting patients well before the medical workers arrived in Libya.


NY Times

New Evidence Disputes Libya Case in H.I.V. Trial

NY Times - 2006-12-07

LONDON, Dec. 6 (Reuters) - Scientists have produced new evidence that casts doubt on charges against five Bulgarian nurses and a Palestinian doctor accused by Libya of deliberately infecting 426 children with the virus that causes AIDS in 1998.


BBC

Study backs Libya HIV case medics

BBC - 2006-12-06

LONDON - Scientists have cast doubt on charges that five Bulgarian nurses and a Palestinian doctor deliberately infected Libyan children with HIV. The medics could face the death penalty if found guilty by a court in Tripoli later this month.


Nature

Molecular HIV evidence backs accused medics

Nature - 2006-12-06

International experts in DNA forensics say that a paper published online by Nature this week provides a firm alibi for the six medical workers facing the death penalty in Libya. The workers have been charged with deliberately infecting more than 400 children with HIV in 1998.



KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), K-RITH Tower Building, Nelson R Mandela School of Medicine, UKZN

Contact: Prof. Tulio de Oliveira, Tel: +27 31 260 4898, Email: tuliodna@gmail.com & deoliveira@ukzn.ac.za

Page design updated 2015. Many of the pages were previously hosted at bioafrica.net.