KRISP changing the status quo and create a scientific environment in South Africa that drives innovations in global health, achieves scientific excellence and reverses the brain drain.



SPOTLIGHT


KRISP Papers


KRISP Papers


Why KRISP?

KRISP NEWS

KRISP at UKZN is reversing brain drain in Africa and achieving scientific excellence!

KRISP at UKZN challenges the status quo to create a scientific environment in (South) Africa that delivers high level science, creates innovations and reverses the brain drain. This vision is starting to pay off, and we are happy to say that in just two years, we published ten manuscripts in Nature, Science and Lancet journals!


Nature paper: Renewing Felsenstein's phylogenetic bootstrap in the era of big data

KRISP Nature paper with Pasteur Institute on a new phylogenetic method to analyse large HIV and mammalian DNA sequence datasets!


Thought Leadership Workshop on Biomedical Innovation and Entrepreneurship - 10 April 2018, Pretoria, South Africa

The Department of Science and Technology (DST) funded Technology Innovation Agency (TIA) in collaboration with KRISP invites academics, government, clinicians, investors, law-makers, entrepreneurs and industrialists to an intellectually engaging exchange of ideas on the establishment of an innovative bio-incubation system. 10 April 2018, Pretoria, South Africa.


Laboratory-free virology research: Computational approaches for evolutionary hypothesis testing

KRISP Talks by Prof. Darren P Martin, IDMM, University of Cape Town (UCT), 9 April 2018 (12:00 - 13:00), K-RITH building, Nelson R Mandela School of Medicine, UKZN, Durban, South Africa. All welcome!


KRISP Newsletter - March 2018: Partnership with TIA, DST and SAMRC on a Thought Leadership Workshop in Pretoria, News, Publications and Collaborators

In our third issue of 2018, we would like to bring attention to a partnership with TIA, DST and SAMRC to deliver a Thought Leadership Workshop on Bio-Innovation. We also highlight some of our publications, collaborators and capacity building workshops


3rd Durban Spark Innovation breakfast meeting - 4th April at 7h30-8h30, Durban, South Africa

In partnership with Stanford University in the United States, UKZN's KZN Research Innovation and Sequencing Platform (KRISP) will host its 3rd Durban Spark Innovation breakfast meeting on the 4th April at 7h30-8h30 K-RITH Tower Building. The keynote address at the third breakfast is Professor Deresh Ramjugernath, UKZN's Deputy Vice-Chancellor of Research.


A dire need to cultivate entrepreneurship and innovation in SA

1 APRIL 2018, by FRED KOCKOTT. South Africa needs to up its game in the world of innovation and entrepreneurship, says University of KwaZulu-Natal deputy vice chancellor: research, Professor Deresh Ramjugernath.


KRISP PAPERS

Renewing Felsenstein's phylogenetic bootstrap in the era of big data.
Lemoine F, Domelevo Entfellner JB, Wilkinson E, Correia D, Davila Felipe M, de Oliveira T, Gascuel O, Nature (2018), :doi:10.1038/s41586-018-0043-0.


Spatial clustering of drug-resistant tuberculosis in Hlabisa subdistrict, KwaZulu-Natal, 2011-2015.
Smith CM, Lessells R, Grant AD, Herbst K, Tanser F, Int J Tuberc Lung Dis. (2018), 1;22(3):287-293. doi: 10.5588/ijtld.17.0457:.


Effect of genetic variation in UGT1A and ABCB1 on moxifloxacin pharmacokinetics in South African patients with tuberculosis.
Naidoo A, Ramsuran V, Chirehwa M, Denti P, McIlleron H, Naidoo K, Yende-Zuma N, Singh R, Ngcapu S, Chaudhry M, Pepper MS, Padayatchi N, Pharmacogenomics (2018), 19(1):17-29. doi: 10.2217/pgs-2017-0144:.


Case report: mechanisms of HIV elite control in two African women.
Moosa Y, Tanko RF, Ramsuran V, Singh R, Madzivhandila M, Yende-Zuma N, Abrahams MR, Selhorst P, Gounder K, Moore PL, Williamson C, Abdool Karim SS, Garrett NJ, Burgers WA, BMC Infect Dis (2018), 18(1):54. doi: 10.1186/s12879-018-2961-8:.


Epidemiological patterns of mental disorders and stigma in a community household survey in urban slum and rural settings in Kenya.
Mutiso VN, Musyimi CW, Tomita A, Loeffen L, Burns JK, Ndetei DM, Int J Soc Psychiatry (2018), 64(2):120-129. doi: 10.1177/0020764017748180:.


KRISP VIDEOS

Krisp - a next generation DNA sequencing research centre opens in Durban, South Africa - eTV news
By: Tulio de Oliveira, Veron Ramsuran, Nicolette Crozier, Zandile Sibisi, Marcel Tongo, Benjamin Chimukangara, Thabiso Dlamini

KRISP TEAM

KRISP BLOGS


Nicolette Crozier, Benjamin Chimukangara, Veron Ramsuran

Meeting of the Swiss, Swedes and South Africans minds


KRISP TOOLS

2016-08-21
Version: 3


REGA HIV Subtyping Tool V3 - South African mirror

This tool is designed to use phylogenetic methods in order to identify the HIV-1 subtype of a specific sequence. The sequence is analysed for recombination using bootscanning methods. The version 3 contains new CRFs (CRF01_AE to CRF47_BF).


2016-08-20
Version: 1


Zika Typing Tool

This is the first version of the Zika typing tool, which uses phylogenetic analysis to identify the species and genotype of the virus.


2016-08-20
Version: 1


Arbovirus Typing Tool

This is the first version of our Arbovirus typing tool for Chikungunya, Dengue, Yellow Fever and Zika


2016-08-20
Version: 1


Chikungunya Typing Tool

This is the first version of the Chikungunya typing tool, which uses phylogenetic analysis to identify the species and genotype of the virus.


2016-08-20
Version: 1


Yellow Fever Virus Typing Tool

This is the first version of the Yellow Fever typing tool, which uses phylogenetic analysis to identify the species and genotype of the virus.


2015-11-06
Version: 1


Dengue Virus Typing Tool

This is a beta version of our Dengue Virus Typing tool. For the mean time, this tool should be used for evaluation only. Please send feedback to Tulio de Oliveira.